Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action (Q30453068)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

0 references

10

object named as

Yves Pommier

1 reference

Europe PubMed Central

13 September 2017

PMC publication ID

2

object named as

John L Nitiss

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

author name string

Dirk Strumberg

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jiaowang Dong

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jerrylaine Walker

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Marc C Nicklaus

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Kurt W Kohn

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jonathan G Heddle

7

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Anthony Maxwell

8

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Siegfried Seeber

9

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

0 references

publication date

1 September 2002

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

46

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

2735-2746

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC127396/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

DNA topoisomerases: structure, function, and mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

DNA gyrase as a drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Mutation of a conserved serine residue in a quinolone-resistant type II topoisomerase alters the enzyme-DNA and drug interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Similarity in the catalysis of DNA breakage and rejoining by type IA and IIA DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Structural similarities between topoisomerases that cleave one or both DNA strands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Topoisomerase IV catalysis and the mechanism of quinolone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Use of a rapid throughput in vivo screen to investigate inhibitors of eukaryotic topoisomerase II enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Type II DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Crystal structure of the breakage-reunion domain of DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

acrB mutation located at carboxyl-terminal region of gyrase B subunit reduces DNA binding of DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

In the presence of subunit A inhibitors DNA gyrase cleaves DNA fragments as short as 20 bp at specific sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Characterization of topoisomerase II-DNA interaction and identification of a DNA-binding domain by ultraviolet laser crosslinking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Structure and mechanism of DNA topoisomerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Drug resistance associated with altered DNA topoisomerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

DNA topoisomerases: essential enzymes and lethal targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

The mechanisms of DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Structure and function of DNA-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

The interaction of Escherichia coli topoisomerase IV with DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Site-specific interaction of DNA gyrase with DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Quinolone-resistant mutations of the gyrA gene of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Nuclease protection by Drosophila DNA topoisomerase II. Enzyme/DNA contacts at the strong topoisomerase II cleavage sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

A structural taxonomy of DNA-binding domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

The molecular basis of quinolone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Topoisomerase-targeting antitumor drugs: mechanisms of cytotoxicity and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

DNA gyrase: purification and catalytic properties of a fragment of gyrase B protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

A topoisomerase from Escherichia coli related to DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

20 June 2018

Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

26 November 2018

A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

26 November 2018

Role of the divalent cation in topoisomerase II mediated reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

26 November 2018

Tryptic fragments of the Escherichia coli DNA gyrase A protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127396

26 November 2018

Footprinting of yeast DNA topoisomerase II lysyl side chains involved in substrate binding and interdomainal interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA Gyrase-Quinolone Complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical applications of quinolones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic inhibitors of DNA topoisomerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the active site tyrosine of Escherichia coli DNA gyrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: relationship with DNA binding affinity and cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of etoposide to topoisomerase II in the absence of DNA: decreased affinity as a mechanism of drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12183223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.46.9.2735-2746.2002

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q30453068&oldid=1975921030"