Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles (Q30468270)

14 September 2017

Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles (English)

1 reference

14 September 2017

Vincent Lin

1

1 reference

14 September 2017

Justin S Golub

2

1 reference

14 September 2017

Tot Bui Nguyen

3

1 reference

14 September 2017

Clifford R Hume

4

1 reference

14 September 2017

Elizabeth C Oesterle

5

1 reference

14 September 2017

Jennifer S Stone

6

1 reference

14 September 2017

language of work or name

English

0 references

publication date

1 October 2011

1 reference

14 September 2017

Journal of Neuroscience

1 reference

14 September 2017

31

1 reference

14 September 2017

43

1 reference

14 September 2017

15329-15339

1 reference

describes a project that uses

14 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3235543/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Cisplatin ototoxicity blocks sensory regeneration in the avian inner ear

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Maintained expression of the planar cell polarity molecule Vangl2 and reformation of hair cell orientation in the regenerating inner ear.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Supporting cell division is not required for regeneration of auditory hair cells after ototoxic injury in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

The canonical Notch signaling pathway: unfolding the activation mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Feathers and fins: non-mammalian models for hair cell regeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Notch regulation of progenitor cell behavior in quiescent and regenerating auditory epithelium of mature birds.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Spontaneous hair cell regeneration in the mouse utricle following gentamicin ototoxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Substrate specificity of gamma-secretase and other intramembrane proteases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Sox2 and JAGGED1 expression in normal and drug-damaged adult mouse inner ear.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Rapid hair cell loss: a mouse model for cochlear lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Hair cell regeneration in the avian auditory epithelium.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

A protocol for rapid generation of recombinant adenoviruses using the AdEasy system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Regulation of cell fate in the sensory epithelia of the inner ear.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Roles of bHLH genes in neural stem cell differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Math1 regulates development of the sensory epithelium in the mammalian cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Math1-driven GFP expression in the developing nervous system of transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Survival of bundleless hair cells and subsequent bundle replacement in the bullfrog's saccule

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Characterization of damage and regeneration in cultured avian utricles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

A new mathematical model for relative quantification in real-time RT-PCR

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

The use of in ovo electroporation for the rapid analysis of neural-specific murine enhancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Autoregulation and multiple enhancers control Math1 expression in the developing nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Math1: an essential gene for the generation of inner ear hair cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Notch signalling pathway mediates hair cell development in mammalian cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Immunocytochemical and morphological evidence for intracellular self-repair as an important contributor to mammalian hair cell recovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Transforming growth factor alpha with insulin stimulates cell proliferation in vivo in adult rat vestibular sensory epithelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Hair cell recovery in the vestibular sensory epithelia of mature guinea pigs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Progenitors of dorsal commissural interneurons are defined by MATH1 expression.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Unconventional myosins in inner-ear sensory epithelia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Inner ear hair cell regeneration in a mammal: identification of a triggering factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Cell division in the gerbil cochlea after acoustic trauma.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Induction of cell proliferation in mammalian inner-ear sensory epithelia by transforming growth factor alpha and epidermal growth factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

New ectopic vestibular hair cell-like cells induced by Math1 gene transfer in postnatal rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Pharmacological inhibition of Notch signaling in the mature guinea pig cochlea

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Comparative morphology of rodent vestibular periphery. I. Saccular and utricular maculae

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Caspase activation in hair cells of the mouse utricle exposed to neomycin.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Notch signalling and the control of cell fate choices in vertebrates.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3235543

Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors

26 November 2018

1 reference

12 December 2020

Stereological study of postnatal development in the mouse utricular macula

1 reference

12 December 2020

Epithelial repair following mechanical injury of the developing organ of Corti in culture: An electron microscopic and autoradiographic study

1 reference

12 December 2020

Notch signalling is needed to maintain, but not to initiate, the formation of prosensory patches in the chick inner ear

1 reference

12 December 2020

Architecture of the mouse utricle: macular organization and hair bundle heights

1 reference

12 December 2020

Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea

1 reference

12 December 2020

Notch signaling and Atoh1 expression during hair cell regeneration in the mouse utricle.

1 reference

12 December 2020

Development of the inner ear of the mouse: a radioautographic study of terminal mitoses

1 reference

12 December 2020

Mammalian vestibular hair cell regeneration

1 reference

12 December 2020

Hair-cell regeneration in organ cultures of the postnatal chicken inner ear.

1 reference

12 December 2020

Ultrastructural evidence for hair cell regeneration in the mammalian inner ear

1 reference

12 December 2020

Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins: implications for gene therapy

1 reference

12 December 2020

10.1523/JNEUROSCI.2057-11.2011

Identifiers

DOI

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

22031879

1 reference