Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux (Q30478990)

16 October 2017

Physiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux (English)

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16 October 2017

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Marta Melar

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16 October 2017

David E Ott

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16 October 2017

Thomas J Hope

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16 October 2017

language of work or name

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22 November 2006

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16 October 2017

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16 October 2017

81

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16 October 2017

4

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16 October 2017

1773-1785

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describes a project that uses

16 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1797554/fullTextXML

inferred from PubMed Central ID database lookup

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Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion

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Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus

20 June 2018

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Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: effects on virologic, immunologic, and toxicity parameters

20 June 2018

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HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process

20 June 2018

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20 June 2018

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Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

20 June 2018

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Exploitation of cellular signaling by HIV-1: unwelcome guests with master keys that signal their entry

20 June 2018

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CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopes

20 June 2018

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Interactions of CCR5 and CXCR4 with CD4 and gp120 in human blood monocyte-derived dendritic cells

20 June 2018

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20 June 2018

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Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes

20 June 2018

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HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells

20 June 2018

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Molecular interactions between extracellular components of the T-cell receptor signaling complex

20 June 2018

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Use of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Fluorescent calcium indicators: subcellular behavior and use in confocal imaging

20 June 2018

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T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: implications for HIV pathogenesis

20 June 2018

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Chemokine receptors and HIV-1: the fusion of two major research fields

20 June 2018

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Human immunodeficiency virus-1 infection requires pertussis toxin sensitive G-protein-coupled signalling and mediates cAMP downregulation

20 June 2018

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CC-chemokines enhance the replication of T-tropic strains of HIV-1 in CD4(+) T cells: role of signal transduction

20 June 2018

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Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway

20 June 2018

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

20 June 2018

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Calcium oscillations increase the efficiency and specificity of gene expression

20 June 2018

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Chemokines--chemotactic cytokines that mediate inflammation

20 June 2018

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Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses

20 June 2018

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Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors

20 June 2018

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Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

20 June 2018

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Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

20 June 2018

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Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor

20 June 2018

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HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

20 June 2018

1 reference

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Kinetics and extent of T cell activation as measured with the calcium signal

20 June 2018

1 reference

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

20 June 2018

1 reference

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The AM and FM of calcium signalling.

20 June 2018

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Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations

20 June 2018

1 reference

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Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

20 June 2018

1 reference

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

20 June 2018

1 reference

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Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

20 June 2018

1 reference

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Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines

20 June 2018

1 reference

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

20 June 2018

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Heterogeneous calcium flux in peripheral T cell subsets revealed by five-color flow cytometry using log-ratio circuitry

20 June 2018

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Photoinactivation and kinetics of membrane fusion mediated by the human immunodeficiency virus type 1 envelope glycoprotein

20 June 2018

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Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding

20 June 2018

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Escherichia coli expression, purification, and biological activity of a truncated soluble CD4.

20 June 2018

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Enzyme-linked immunoassay for human immunodeficiency virus type 1 envelope glycoprotein 120.

20 June 2018

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Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus

20 June 2018

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20 June 2018

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CXCR4 heterogeneity in primary cells: possible role of ubiquitination.

20 June 2018

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Direct observation of ligand recognition by T cells.

26 November 2018

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Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels

26 November 2018

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Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection

26 November 2018

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CXCR4 and CCR5 expression delineates targets for HIV-1 disruption of T cell differentiation.

26 November 2018

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Expression patterns of the HIV type 1 coreceptors CCR5 and CXCR4 on CD4+ T cells and monocytes from cord and adult blood

26 November 2018

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12 December 2020

Distinct biochemical signals characterize agonist- and altered peptide ligand-induced differentiation of naive CD4+ T cells into Th1 and Th2 subsets

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Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes

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The role of the CD4 receptor versus HIV coreceptors in envelope-mediated apoptosis in peripheral blood mononuclear cells

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Functional Genomic Analysis of the Response of HIV‐1–Infected Lymphatic Tissue to Antiretroviral Therapy

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Identifiers

DOI

10.1128/JVI.01316-06

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

17121788

1 reference