Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac. (Q30480399)

12 August 2017

Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac. (English)

1 reference

12 August 2017

Shiro Suetsugu

1

1 reference

12 August 2017

Shusaku Kurisu

2

1 reference

12 August 2017

Tsukasa Oikawa

3

1 reference

12 August 2017

Daisuke Yamazaki

4

1 reference

12 August 2017

Atsushi Oda

5

1 reference

12 August 2017

Tadaomi Takenawa

6

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12 August 2017

language of work or name

English

0 references

publication date

15 May 2006

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12 August 2017

15

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based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

173

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12 August 2017

4

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12 August 2017

571-585

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2063866/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation

28 July 2018

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Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases

28 July 2018

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Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

28 July 2018

1 reference

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Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53

28 July 2018

1 reference

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Magic touch: how does cell-cell adhesion trigger actin assembly?

28 July 2018

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Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels

28 July 2018

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PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

28 July 2018

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Purification and architecture of the ubiquitous Wave complex

28 July 2018

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Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation

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Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

28 July 2018

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Cell migration: integrating signals from front to back

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Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions

28 July 2018

1 reference

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Molecular requirements for actin-based lamella formation in Drosophila S2 cells

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WAVE2 is required for directed cell migration and cardiovascular development

28 July 2018

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WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility

28 July 2018

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Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

28 July 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

28 July 2018

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Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

28 July 2018

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N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

28 July 2018

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Signaling pathways controlling cell polarity and chemotaxis

28 July 2018

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WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

28 July 2018

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Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin

28 July 2018

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IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

28 July 2018

1 reference

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Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

28 July 2018

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Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling

28 July 2018

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Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

28 July 2018

1 reference

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Rho GTPases and the actin cytoskeleton

28 July 2018

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Abi1 is essential for the formation and activation of a WAVE2 signalling complex

28 July 2018

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Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells.

21 January 2018

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Regulation of cortical actin networks in cell migration.

21 January 2018

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Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration

21 January 2018

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A novel function of WAVE in lamellipodia: WAVE1 is required for stabilization of lamellipodial protrusions during cell spreading

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16702231

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200509067

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

16702231

1 reference