Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C (Q30480589)

12 August 2017

Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C (English)

1 reference

positive regulation of G2/M transition of mitotic cell cycle

12 August 2017

1 reference

GOA release 2020-03-11

1 reference

Jonathon Noe Joseph Pines

GOA release 2020-03-11

author

series ordinal

2

1 reference

22 June 2017

Barbara Di Fiore

1

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 May 2007

1 reference

12 August 2017

13

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

12 August 2017

177

1 reference

12 August 2017

425-437

1 reference

12 August 2017

3

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064829/fullTextXML

inferred from PubMed Central ID database lookup

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Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

28 July 2018

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28 July 2018

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Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells

28 July 2018

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The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1

28 July 2018

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The anaphase-promoting complex: a key factor in the regulation of cell cycle

28 July 2018

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Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

28 July 2018

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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

28 July 2018

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Regulation of early events in chromosome replication

28 July 2018

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Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

28 July 2018

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Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis

28 July 2018

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Loss of Geminin induces rereplication in the presence of functional p53

28 July 2018

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Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

28 July 2018

1 reference

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Mitotic regulation of the human anaphase-promoting complex by phosphorylation

28 July 2018

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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

28 July 2018

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Cyclin E ablation in the mouse

28 July 2018

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Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

28 July 2018

1 reference

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

28 July 2018

1 reference

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Active cyclin B1-Cdk1 first appears on centrosomes in prophase

28 July 2018

1 reference

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The anaphase-promoting complex: it's not just for mitosis any more.

28 July 2018

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Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

28 July 2018

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The anaphase-promoting complex: proteolysis in mitosis and beyond

28 July 2018

1 reference

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E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

28 July 2018

1 reference

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

28 July 2018

1 reference

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A system for stable expression of short interfering RNAs in mammalian cells

28 July 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

28 July 2018

1 reference

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Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

28 July 2018

1 reference

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Early expressed Clb proteins allow accumulation of mitotic cyclin by inactivating proteolytic machinery during S phase

28 July 2018

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Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

28 July 2018

1 reference

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A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

28 July 2018

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Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

28 July 2018

1 reference

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Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

28 July 2018

1 reference

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Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

28 July 2018

1 reference

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Mitotic regulation of the APC activator proteins CDC20 and CDH1

28 July 2018

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Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

28 July 2018

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Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

28 July 2018

1 reference

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Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

28 July 2018

1 reference

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Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles

28 July 2018

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Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.

28 July 2018

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The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

28 July 2018

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Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

28 July 2018

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Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.

28 July 2018

1 reference

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Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064829

Mapping replicational sites in the eucaryotic cell nucleus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064829

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064829

Pulling the string: cell cycle regulation during Drosophila development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064829

Temporal and spatial control of cyclin B1 destruction in metaphase

28 July 2018

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Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611166

Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611166

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611166

Mouse emi1 has an essential function in mitotic progression during early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611166

Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611166

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17485488

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200611166

1 reference

release_qfswxu7jdvdqzgwnhh6d5x77mq

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qfswxu7jdvdqzgwnhh6d5x77mq

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

1 reference