Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). (Q30480596)

12 August 2017

Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). (English)

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12 August 2017

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Jamie M Keck

1

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12 August 2017

Matthew K Summers

2

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12 August 2017

Donato Tedesco

3

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12 August 2017

Susanna Ekholm-Reed

4

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12 August 2017

Li-Chiou Chuang

5

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12 August 2017

Peter K Jackson

6

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12 August 2017

Steven I Reed

7

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12 August 2017

language of work or name

English

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publication date

1 July 2007

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12 August 2017

Journal of Cell Biology

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12 August 2017

178

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12 August 2017

3

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12 August 2017

371-385

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describes a project that uses

12 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064850/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064850/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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Cyclin E dysregulation and chromosomal instability in endometrial cancer.

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The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

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Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.

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Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

21 January 2018

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Cyclin E expression and proliferation in breast cancer.

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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12 December 2020

Regulated separation of sister centromeres depends on the spindle assembly checkpoint but not on the anaphase promoting complex/cyclosome

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12 December 2020

Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland

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12 December 2020

Deregulation of the cell cycle in cancer

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12 December 2020

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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12 December 2020

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

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12 December 2020

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

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12 December 2020

Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila

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12 December 2020

Separase is required at multiple pre-anaphase cell cycle stages in human cells

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12 December 2020

Deregulation of cyclin E in breast cancer

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12 December 2020

Identifiers

DOI

10.1083/JCB.200703202

1 reference

12 August 2017

1 reference

12 August 2017

1 reference