Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box. (Q30488315)

13 August 2017

Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box. (English)

1 reference

13 August 2017

1 reference

metastatic osteosarcoma

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Daisy D Colón-López

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Eric Glasgow

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jürgen Bosch

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Sung-Hyeok Hong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jenny Han

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Tsion Z Minas

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Matthew Swift

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Mikell Paige

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jeffrey A Toretsky

10

1 reference

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2 June 2020

Aykut Üren

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Yasemin Saygideger Kont

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

1 reference

10 September 2015

1 reference

Molecular Cancer Therapeutics

13 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

14

1 reference

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2 June 2020

issue

11

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2 June 2020

page(s)

2497-2507

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level

2 June 2020

cites work

1 reference

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Plasmodium vivax inhibits erythroid cell growth through altered phosphorylation of the cytoskeletal protein ezrin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Recurrent osteosarcoma with a single pulmonary metastasis: a multi-institutional review.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Translational biology of osteosarcoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

20 June 2018

ERM proteins at a glance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Role of ezrin in osteosarcoma metastasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

ERM proteins in cancer progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

The open access malaria box: a drug discovery catalyst for neglected diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

A member of the Plasmodium falciparum PHIST family binds to the erythrocyte cytoskeleton component band 4.1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

The ezrin metastatic phenotype is associated with the initiation of protein translation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Cytoskeletal and membrane remodelling during malaria parasite invasion of the human erythrocyte

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Addition of pamidronate to chemotherapy for the treatment of osteosarcoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Hallmarks of Cancer: The Next Generation

20 June 2018

1 reference

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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

20 June 2018

1 reference

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Modeling metastasis biology and therapy in real time in the mouse lung.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Chemical genetics of Plasmodium falciparum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Thousands of chemical starting points for antimalarial lead identification

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Quinolines and structurally related heterocycles as antimalarials

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Organizing the cell cortex: the role of ERM proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Pediatric osteogenic sarcoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Drug development against metastasis-related genes and their pathways: A rationale for cancer therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Metastasis: a therapeutic target for cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Metastasis: recent discoveries and novel treatment strategies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

New signals from the invasive front

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Biology and therapeutic advances for pediatric osteosarcoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

ERM proteins and merlin: integrators at the cell cortex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Molecular properties that influence the oral bioavailability of drug candidates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Stages of embryonic development of the zebrafish

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-implications for the fish embryo test (FET).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Comparison of Shape-Matching and Docking as Virtual Screening Tools

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

Identification of regulators of germ layer morphogenesis using proteomics in zebrafish

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4636458

The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26358752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Osteogenic sarcoma with clinically detectable metastasis at initial presentation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26358752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Treatment of metastatic osteosarcoma at diagnosis: a Pediatric Oncology Group Study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26358752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-15-0511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

26358752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26358752%20AND%20SRC:MED&resulttype=core&format=json