The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. (Q30490027)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18798283%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity (English)

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14 January 2020

4

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14 January 2020

author name string

Nichole E LaPointe

1

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14 January 2020

Gerardo Morfini

2

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14 January 2020

Gustavo Pigino

3

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14 January 2020

Alan P Kozikowski

5

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14 January 2020

Lester I Binder

6

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14 January 2020

Scott T Brady

7

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14 January 2020

publication date

1 February 2009

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Journal of Neuroscience Research

14 January 2020

published in

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14 January 2020

volume

87

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14 January 2020

issue

2

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14 January 2020

page(s)

440-451

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1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C

14 January 2020

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Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

28 July 2018

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Tau polymerization: role of the amino terminus

28 July 2018

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Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

28 July 2018

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Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

28 July 2018

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Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

28 July 2018

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Domains of neuronal microtubule-associated proteins and flexural rigidity of microtubules

28 July 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

28 July 2018

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Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

28 July 2018

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Monomer-polymer equilibria in the axon: direct measurement of tubulin and actin as polymer and monomer in axoplasm

28 July 2018

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Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors

28 July 2018

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Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms

28 July 2018

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The microtubule binding domain of tau protein.

28 July 2018

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Epitopes that span the tau molecule are shared with paired helical filaments.

28 July 2018

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A novel brain ATPase with properties expected for the fast axonal transport motor

28 July 2018

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28 July 2018

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Structure-based design leads to the identification of lithium mimetics that block mania-like effects in rodents. possible new GSK-3beta therapies for bipolar disorders

28 July 2018

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Tau binding to microtubules does not directly affect microtubule-based vesicle motility.

26 November 2018

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26 November 2018

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NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

26 November 2018

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26 November 2018

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26 November 2018

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Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

26 November 2018

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Novel isoforms of tau that lack the microtubule-binding domain

26 November 2018

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A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

26 November 2018

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Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.

26 November 2018

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Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.

26 November 2018

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Fast axonal transport misregulation and Alzheimer's disease

26 November 2018

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An R5L tau mutation in a subject with a progressive supranuclear palsy phenotype.

26 November 2018

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Single-molecule investigation of the interference between kinesin, tau and MAP2c

26 November 2018

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c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

26 November 2018

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Late-onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation

26 November 2018

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Glycogen synthase kinase-3beta is complexed with tau protein in brain microtubules

26 November 2018

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C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.

26 November 2018

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Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

26 November 2018

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Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein Tau.

26 November 2018

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Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure

26 November 2018

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GTP gamma S inhibits organelle transport along axonal microtubules

26 November 2018

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Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.

26 November 2018

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A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins

26 November 2018

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12 December 2020

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment

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12 December 2020

Domains of tau protein and interactions with microtubules

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12 December 2020

Use of a synthetic peptide as a selective substrate for glycogen synthase kinase 3

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12 December 2020

The 'jaws' model of tau-microtubule interaction examined in CHO cells

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12 December 2020

Topographic regulation of cytoskeletal protein phosphorylation by multimeric complexes in the squid giant fiber system

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12 December 2020

Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms

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12 December 2020

N-terminal fragments of tau inhibit full-length tau polymerization in vitro

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12 December 2020

Identifiers

DOI

10.1002/JNR.21850

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18798283%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18798283%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18798283

1 reference