Presenilin-2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's disease (Q30497860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Presenilin-2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's disease (English)

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20 January 2020

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2

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20 January 2020

author name string

Toshihiko Toda

1

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20 January 2020

Genzo Ito

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Masahiro Maeda

4

1 reference

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20 January 2020

Takahiko Shimizu

5

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20 January 2020

publication date

29 December 2010

1 reference

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Journal of Biomedicine and Biotechnology

20 January 2020

published in

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20 January 2020

volume

2011

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20 January 2020

page(s)

617974

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Creative Commons Attribution 3.0 Unported

20 January 2020

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

cites work

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Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

20 June 2018

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20 June 2018

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

20 June 2018

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21 January 2018

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Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.

21 January 2018

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Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease

21 January 2018

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Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

21 January 2018

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21 January 2018

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PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

21 January 2018

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Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21234330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transgenic mouse models of Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21234330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2011/617974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

21234330

1 reference