Age-related alterations in the dynamic behavior of microglia (Q30498664)

14 October 2017

Age-related alterations in the dynamic behavior of microglia (English)

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14 October 2017

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14 October 2017

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Lian Zhao

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14 October 2017

Mausam R Damani

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14 October 2017

Aurora M Fontainhas

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14 October 2017

Juan Amaral

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14 October 2017

Robert N Fariss

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14 October 2017

29 December 2010

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14 October 2017

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263-276

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describes a project that uses

14 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3056927/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

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In vivo observation of the locomotion of microglial cells in the retina

20 June 2018

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Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge

20 June 2018

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Inflammation in neurodegenerative diseases

20 June 2018

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Microglia in the aging brain: relevance to neurodegeneration

20 June 2018

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Microglia in neurodegenerative disease

20 June 2018

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P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP

20 June 2018

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Age-associated declines in immune system development and function: causes, consequences, and reversal

20 June 2018

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The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages.

20 June 2018

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Para-inflammation in the aging retina.

20 June 2018

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Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease

20 June 2018

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Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling

20 June 2018

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Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

20 June 2018

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Exploring the full spectrum of macrophage activation

20 June 2018

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Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury

20 June 2018

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Origin and physiological roles of inflammation

20 June 2018

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Microglial degeneration in the aging brain--bad news for neurons?

20 June 2018

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Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy

20 June 2018

1 reference

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Retinal microglia and uveal tract dendritic cells and macrophages are not CX3CR1 dependent in their recruitment and distribution in the young mouse eye.

20 June 2018

1 reference

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In vivo visualization of dendritic cells, macrophages, and microglial cells responding to laser-induced damage in the fundus of the eye.

20 June 2018

1 reference

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Neuronal 'On' and 'Off' signals control microglia

20 June 2018

1 reference

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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

20 June 2018

1 reference

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Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

20 June 2018

1 reference

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Turnover of resident retinal microglia in the normal adult mouse.

20 June 2018

1 reference

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Microglia derived from aging mice exhibit an altered inflammatory profile.

20 June 2018

1 reference

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The P2Y12 receptor regulates microglial activation by extracellular nucleotides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Like cops on the beat: the active role of resting microglia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

ATP mediates rapid microglial response to local brain injury in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes

20 June 2018

1 reference

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Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators.

20 June 2018

1 reference

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Gene regulation and DNA damage in the ageing human brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

New insights into neuron-glia communication

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Microglial activation by purines and pyrimidines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Molecular signals for glial activation: pro- and anti-inflammatory cytokines in the injured brain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Confocal imaging of microglial cell dynamics in hippocampal slice cultures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Receptors for purines and pyrimidines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Microglial expression of MHC class II increases in normal aging of nonhuman primates.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Altered antigen expression of microglia in the aged rodent CNS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Effects of ageing on microglia in the normal rat brain: immunohistochemical observations.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Signalling via ATP in the nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Turnover of resident microglia in the normal adult mouse brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Standardized full-field electroretinography. Normal values and their variation with age

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056927

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

20 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Inflammation and breakdown of the blood-retinal barrier during "physiological aging" in the rat retina: a model for CNS aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Evidence that aging and amyloid promote microglial cell senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Structure-function analysis of rods and cones in juvenile, adult, and aged C57bl/6 and Balb/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Characteristics of bone marrow-derived microglia in the normal and injured retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Microglial activation, emergence of ED1-expressing cells and clusterin upregulation in the aging rat CNS, with special reference to the spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Intracerebral hemorrhage-induced brain injury is aggravated in senescence-accelerated prone mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Microglia density decreases with age in a mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Enlarged and phagocytic, but not primed, interleukin-1 alpha-immunoreactive microglia increase with age in normal human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Dystrophic microglia in the aging human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

White matter injury in young and aged rats after intracerebral hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Glial responses, neuron death and lesion resolution after intracerebral hemorrhage in young vs. aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2010.00660.X

Influence of age on the production and regulation of interleukin-1 in mice

21 January 2018

1 reference

12 December 2020

Gene-expression profile of the ageing brain in mice

1 reference

12 December 2020

Activated microglia in the human glaucomatous optic nerve head

1 reference

12 December 2020

Embryonic and postnatal development of microglial cells in the mouse retina

1 reference

12 December 2020

10.1111/J.1474-9726.2010.00660.X

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference