Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates. (Q30498692)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21112353%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates (English)

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17 January 2020

0 references

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2

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17 January 2020

author name string

Tatyana Verina

series ordinal

1

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17 January 2020

Jay S Schneider

series ordinal

3

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17 January 2020

Tomás R Guilarte

series ordinal

4

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17 January 2020

publication date

26 November 2010

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17 January 2020

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17 January 2020

volume

32

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17 January 2020

issue

2

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17 January 2020

page(s)

215-226

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Manganese and Parkinson's disease: a critical review and new findings

17 January 2020

cites work

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Brain iron homeostasis and neurodegenerative disease

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Manganese neurotoxicity: lessons learned from longitudinal studies in nonhuman primates

20 June 2018

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Effects of chronic manganese exposure on working memory in non-human primates

20 June 2018

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Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism

20 June 2018

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Microglial degeneration in the aging brain--bad news for neurons?

20 June 2018

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Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates

20 June 2018

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

20 June 2018

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The neuropathology of manganese-induced Parkinsonism

20 June 2018

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Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.

20 June 2018

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Microglia derived from aging mice exhibit an altered inflammatory profile.

20 June 2018

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Effects of chronic manganese exposure on cognitive and motor functioning in non-human primates

20 June 2018

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Microglial senescence: does the brain's immune system have an expiration date?

20 June 2018

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Ferritin levels in microglia depend upon activation: modulation by reactive oxygen species

20 June 2018

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Microglia in the aging brain

20 June 2018

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Manganese neurotoxicity: connecting the dots along the continuum of dysfunction

20 June 2018

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Manganese dosimetry: species differences and implications for neurotoxicity

20 June 2018

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Oxidation-induced ferritin turnover in microglial cells: role of proteasome.

20 June 2018

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Iron, brain ageing and neurodegenerative disorders

20 June 2018

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A nuclear microscopic and histochemical study of iron concentrations and distribution in the midbrain of two age groups of monkeys unilaterally injected with MPTP.

20 June 2018

1 reference

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Imaging end points for monitoring neuroprotection in Parkinson's disease.

20 June 2018

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Staging of brain pathology related to sporadic Parkinson's disease

20 June 2018

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Brain iron metabolism and neurodegenerative disorders

20 June 2018

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Dopamine transporter density is decreased in parkinsonian patients with a history of manganese exposure: what does it mean?

20 June 2018

1 reference

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Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells

20 June 2018

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Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

20 June 2018

1 reference

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Manganese neurotoxicity: a mechanistic hypothesis.

20 June 2018

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Alteration of iron homeostasis following chronic exposure to manganese in rats

20 June 2018

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Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy

20 June 2018

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Manganese inhibits mitochondrial aconitase: a mechanism of manganese neurotoxicity

20 June 2018

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

20 June 2018

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20 June 2018

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Relationship of iron to oligodendrocytes and myelination

20 June 2018

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Distribution of iron in the basal ganglia and neocortex in postmortem tissue in Parkinson's disease and Alzheimer's disease

20 June 2018

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Isoforms of ferritin have a specific cellular distribution in the brain

20 June 2018

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Complex I, iron, and ferritin in Parkinson's disease substantia nigra

20 June 2018

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Brain iron: location and function

20 June 2018

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Inducible nitric oxide synthase activity of cloned murine microglial cells

20 June 2018

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A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains

20 June 2018

1 reference

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Altered brain metabolism of iron as a cause of neurodegenerative diseases?

20 June 2018

1 reference

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Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias).

20 June 2018

1 reference

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Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseases

20 June 2018

1 reference

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Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brain

20 June 2018

1 reference

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L-dopa treatment and Parkinson's disease

20 June 2018

1 reference

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Production of superoxide anions by a CNS macrophage, the microglia

20 June 2018

1 reference

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Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

20 June 2018

1 reference

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Brain iron and ferritin in Parkinson's and Alzheimer's diseases.

20 June 2018

1 reference

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Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

20 June 2018

1 reference

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Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

20 June 2018

1 reference

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A histochemical study of iron, transferrin, and ferritin in Alzheimer's diseased brains.

20 June 2018

1 reference

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Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease

20 June 2018

1 reference

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Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin

20 June 2018

1 reference

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Ultrastructural localization of nonheme celluar iron with ferrocyanide

20 June 2018

1 reference

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Elevated manganese levels associated with dementia and extrapyramidal signs

20 June 2018

1 reference

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Parkinsonism and dystonia caused by the illicit use of ephedrone--a longitudinal study

20 June 2018

1 reference

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Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057349

Methamphetamine increases basal ganglia iron to levels observed in aging

26 November 2018

1 reference

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Evidence that aging and amyloid promote microglial cell senescence.

26 November 2018

1 reference

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Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057349

Cellular iron status influences the functional relationship between microglia and oligodendrocytes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057349

Nigrostriatal dopamine system dysfunction and subtle motor deficits in manganese-exposed non-human primates.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057349

Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation.

26 November 2018

1 reference

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Distribution of divalent metal transporter-1 in the monkey basal ganglia

26 November 2018

1 reference

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Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain

26 November 2018

1 reference

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Dystrophic microglia in the aging human brain

26 November 2018

1 reference

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Dopamine transporter binding in chronic manganese intoxication

26 November 2018

1 reference

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Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate.

26 November 2018

1 reference

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H and L ferritin subunit mRNA expression differs in brains of control and iron-deficient rats.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057349

Release of iron from ferritin by metabolites of benzene and superoxide radical generating agents

26 November 2018

1 reference

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Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury.

26 November 2018

1 reference

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MRI evaluation of brain iron in earlier- and later-onset Parkinson's disease and normal subjects.

26 November 2018

1 reference

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Cellular distribution of ferritin subunits in postnatal rat brain.

26 November 2018

1 reference

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Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits.

26 November 2018

1 reference

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Cellular management of iron in the brain.

26 November 2018

1 reference

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Dopaminergic system activity and cellular defense mechanisms in the striatum and striatal synaptosomes of the rat subchronically exposed to manganese.

26 November 2018

1 reference

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Effects of manganese oxide on monkeys as revealed by a combined neurochemical, histological and neurophysiological evaluation.

26 November 2018

1 reference

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The Pivotal Role of Iron in NF-kappaB Activation and Nigrostriatal Dopaminergic Neurodegeneration: Prospects for Neuroprotection in Parkinson's Disease with Iron Chelators

26 November 2018

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12 December 2020

Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia

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12 December 2020

Effect of levodopa treatment for parkinsonism in welders: A double-blind study

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12 December 2020

A new immunoperoxidase marker for microglia in paraffin section

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12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

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12 December 2020

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

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12 December 2020

The regional distribution and cellular localization of iron in the rat brain

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12 December 2020

10.1016/J.NEURO.2010.11.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21112353%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21112353%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21112353

1 reference