Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling (Q30499169)

12 October 2017

Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling (English)

1 reference

12 October 2017

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C G Diniz Behn

1

1 reference

12 October 2017

N Kopell

2

1 reference

12 October 2017

E N Brown

3

1 reference

12 October 2017

T Mochizuki

4

1 reference

12 October 2017

T E Scammell

5

1 reference

12 October 2017

language of work or name

English

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publication date

16 April 2008

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Journal of Neurophysiology

12 October 2017

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12 October 2017

99

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12 October 2017

6

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12 October 2017

3090-3103

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Orexin/hypocretin modulation of the basal forebrain cholinergic system: insights from in vivo microdialysis studies

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Mathematical model of network dynamics governing mouse sleep-wake behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Narcolepsy with cataplexy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Developmental divergence of sleep-wake patterns in orexin knockout and wild-type mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

A quartet neural system model orchestrating sleep and wakefulness mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Hypothalamic regulation of sleep and circadian rhythms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Dynamics of sleep-wake cyclicity in developing rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Common scale-invariant patterns of sleep-wake transitions across mammalian species.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Behavioral state instability in orexin knock-out mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

The nature of arousal in sleep.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Activity of dorsal raphe cells across the sleep-waking cycle and during cataplexy in narcoleptic dogs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

The neurobiology, diagnosis, and treatment of narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Selective activation of the extended ventrolateral preoptic nucleus during rapid eye movement sleep.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Direct and indirect excitation of laterodorsal tegmental neurons by Hypocretin/Orexin peptides: implications for wakefulness and narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Orexins/hypocretins excite basal forebrain cholinergic neurones

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Orexin A and B evoke noradrenaline release from rat cerebrocortical slices

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

The sleep switch: hypothalamic control of sleep and wakefulness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Arousal effect of orexin A depends on activation of the histaminergic system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Hypocretin/orexin, sleep and narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Discharge patterns of neurons in cholinergic regions of the basal forebrain during waking and sleep

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Neurons containing hypocretin (orexin) project to multiple neuronal systems

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Noradrenaline inhibits preoptic sleep-active neurons through alpha 2-receptors in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Discharge of noradrenergic locus coeruleus neurons in behaving rats and monkeys suggests a role in vigilance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

A neural circuit for circadian regulation of arousal.

20 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Single cell activity patterns of pedunculopontine tegmentum neurons across the sleep-wake cycle in the freely moving rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Sleep states alter activity of suprachiasmatic nucleus neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Long-term vs. short-term processes regulating REM sleep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Identification of sleep-promoting neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Differential target-dependent actions of coexpressed inhibitory dynorphin and excitatory hypocretin/orexin neuropeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Behavioral correlates of activity in identified hypocretin/orexin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Suprachiasmatic modulation of noradrenaline release in the ventrolateral preoptic nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Nicotinic enhancement of the noradrenergic inhibition of sleep-promoting neurons in the ventrolateral preoptic area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Locus coeruleus neurons: cessation of activity during cataplexy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.01243.2007

Circadian and Homeostatic Regulation of Hypocretin in a Primate Model: Implications for the Consolidation of Wakefulness

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Afferents to the ventrolateral preoptic nucleus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Orexin (hypocretin) neurons contain dynorphin.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065358

Circadian regulation of sleep in mammals: role of the suprachiasmatic nucleus

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18417630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/JN.01243.2007

1 reference

12 October 2017

1 reference

12 October 2017

1 reference