Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents (Q30514535)

18 October 2017

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents (English)

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18 October 2017

2

Freda H Passam

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18 October 2017

Reema Jasuja

1

1 reference

18 October 2017

Daniel R Kennedy

3

1 reference

18 October 2017

Sarah H Kim

4

1 reference

18 October 2017

Lotte van Hessem

5

1 reference

18 October 2017

Lin Lin

6

1 reference

18 October 2017

Sheryl R Bowley

7

1 reference

18 October 2017

Sucharit S Joshi

8

1 reference

18 October 2017

James R Dilks

9

1 reference

18 October 2017

Bruce Furie

10

1 reference

18 October 2017

Barbara C Furie

11

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18 October 2017

Robert Flaumenhaft

12

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18 October 2017

language of work or name

English

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publication date

8 May 2012

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Journal of Clinical Investigation

18 October 2017

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18 October 2017

122

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18 October 2017

6

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18 October 2017

2104-2113

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P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Discovery of a small molecule PDI inhibitor that inhibits reduction of HIV-1 envelope glycoprotein gp120.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Laser-induced endothelial cell activation supports fibrin formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Bacitracin is not a specific inhibitor of protein disulfide isomerase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Interaction and functional association of protein disulfide isomerase with alphaVbeta3 integrin on endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Characterization of redox state and reductase activity of protein disulfide isomerase under different redox environments using a sensitive fluorescent assay

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Allosteric disulfide bonds in thrombosis and thrombolysis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Disulfide isomerization switches tissue factor from coagulation to cell signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

A high-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Cell-surface protein disulfide isomerase catalyzes transnitrosation and regulates intracellular transfer of nitric oxide.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Role of dietary flavonoids in protection against cancer and coronary heart disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

The affinity of troxerutin for the venous wall measured by laser scanning microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Uptake and localisation of O-(beta-hydroxyethyl)-rutosides in the venous wall, measured by laser scanning microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Protein disulphide isomerase in platelet function.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Absorption of quercetin and rutin in rat small intestine

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Mechanisms involved in the antiplatelet activity of rutin, a glycoside of the flavonol quercetin, in human platelets

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366406

Physical proximity and functional association of glycoprotein 1balpha and protein-disulfide isomerase on the platelet plasma membrane

26 November 2018

1 reference

12 December 2020

Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes

1 reference

12 December 2020

Protein disulfide isomerase mediates integrin-dependent adhesion

1 reference

12 December 2020

Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway

1 reference

12 December 2020

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

1 reference

12 December 2020

Monoclonal antibodies to a synthetic fibrin-like peptide bind to human fibrin but not fibrinogen

1 reference

12 December 2020

Pharmacokinetics and metabolism of oral diosmin in healthy volunteers

1 reference

12 December 2020

Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study

1 reference

12 December 2020

Exposure of the cryptic Arg-Gly-Asp sequence in thrombospondin-1 by protein disulfide isomerase

1 reference

12 December 2020

Protein disulphide isomerase mediates platelet aggregation and secretion

1 reference

12 December 2020

Evidence for activation of tissue factor by an allosteric disulfide bond

1 reference

12 December 2020

Imaging fibrin formation and platelet and endothelial cell activation in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI61228

1 reference

18 October 2017

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18 October 2017

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