Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood (Q30544793)

18 August 2017

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood (English)

1 reference

18 August 2017

Ana Pocivavsek

1

1 reference

18 August 2017

Hui-Qiu Wu

2

1 reference

18 August 2017

Greg I Elmer

3

1 reference

18 August 2017

John P Bruno

4

1 reference

18 August 2017

Robert Schwarcz

5

1 reference

18 August 2017

language of work or name

English

0 references

publication date

20 April 2012

1 reference

European Journal of Neuroscience

18 August 2017

1 reference

18 August 2017

35

1 reference

18 August 2017

10

1 reference

18 August 2017

1605-1612

1 reference

Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Exposure to kynurenic acid during adolescence produces memory deficits in adulthood

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Characterization of the cognitive impairments induced by prenatal exposure to stress in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

The Hippocampal Formation in Schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Epidemiology-driven neurodevelopmental animal models of schizophrenia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Animal models of gene-environment interactions in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

The dynamic effects of nicotine on the developing brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Neural basis of psychosis-related behaviour in the infection model of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Elevations of endogenous kynurenic acid produce spatial working memory deficits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Monitoring tryptophan metabolism in chronic immune activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Impaired passive avoidance learning in mice lacking central neuronal nicotinic acetylcholine receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Schizophrenia as a disorder of neurodevelopment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Increased cortical kynurenate content in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Early postnatal stimulation influences passive avoidance behaviour of adult rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

GABAA, NMDA and AMPA receptors: a developmentally regulated 'ménage à trois'.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Developments of a water-maze procedure for studying spatial learning in the rat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

l-Kynurenine Its synthesis and possible regulatory function in brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Implications of normal brain development for the pathogenesis of schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Nicotinylalanine increases the formation of kynurenic acid in the brain and antagonizes convulsions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

Passive avoidance learning in the rat as functions of d-amphetamine dosage and shock intensity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773083

The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents

20 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Endogenous kynurenic acid disrupts prepulse inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Intrahippocampal infusion of the NMDA receptor antagonist AP5 impairs retention of an inhibitory avoidance task: protection from impairment by pretraining or preexposure to the task apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08064.X

The functional importance of increased brain tryptophan in the serotonergic response to restraint stress

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22515201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The continuing problem of false positives in repeated measures ANOVA in psychophysiology: a multivariate solution

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22515201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22515201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1460-9568.2012.08064.X

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

22515201

1 reference