Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium (Q30612009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378587%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium (English)

1 reference

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22 February 2020

0 references

1

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22 February 2020

author name string

Li Xuan Tan

2

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22 February 2020

Zhichun Jiang

3

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22 February 2020

Roxana A Radu

4

1 reference

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22 February 2020

Aparna Lakkaraju

5

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22 February 2020

publication date

5 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378587%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

22 February 2020

published in

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22 February 2020

volume

26

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22 February 2020

issue

1

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22 February 2020

page(s)

1-14

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Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration

22 February 2020

cites work

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20 June 2018

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IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration

20 June 2018

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Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide

20 June 2018

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p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium

20 June 2018

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20 June 2018

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Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

20 June 2018

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Functional interaction between autophagy and ciliogenesis

20 June 2018

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20 June 2018

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Noncanonical autophagy promotes the visual cycle

20 June 2018

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20 June 2018

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Autophagy and microtubules - new story, old players.

20 June 2018

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Balance between autophagic pathways preserves retinal homeostasis

20 June 2018

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Autophagy in human health and disease

20 June 2018

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Autophagy protects the retina from light-induced degeneration

20 June 2018

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20 June 2018

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Mechanism of polarized lysosome exocytosis in epithelial cells

20 June 2018

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Guidelines for the use and interpretation of assays for monitoring autophagy

20 June 2018

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Mechanisms of age-related macular degeneration

20 June 2018

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Characterization of an apical ceramide-enriched compartment regulating ciliogenesis

20 June 2018

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The bisretinoids of retinal pigment epithelium

20 June 2018

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Canonical and non-canonical autophagy: variations on a common theme of self-eating?

20 June 2018

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Severe alterations in lipid composition of frontal cortex lipid rafts from Parkinson's disease and incidental Parkinson's disease

20 June 2018

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Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration

20 June 2018

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Autophagy activation in the injured photoreceptor inhibits fas-mediated apoptosis.

20 June 2018

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mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications

20 June 2018

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Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation

20 June 2018

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20 June 2018

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Altered lipid content inhibits autophagic vesicular fusion

20 June 2018

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20 June 2018

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Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

20 June 2018

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20 June 2018

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Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking

20 June 2018

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The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

20 June 2018

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20 June 2018

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Autophagy is one of the multiple mechanisms active in photoreceptor degeneration

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

20 June 2018

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Focal adhesion kinase (p125FAK) and paxillin are substrates for sphingomyelinase-induced tyrosine phosphorylation in Swiss 3T3 fibroblasts

20 June 2018

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The retinal pigment epithelium: a versatile partner in vision.

20 June 2018

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Apoptosis and autophagy in photoreceptors exposed to oxidative stress.

20 June 2018

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Wip1-dependent regulation of autophagy, obesity, and atherosclerosis.

21 January 2018

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Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect.

21 January 2018

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Is medication use associated with the incidence of early age-related maculopathy? Pooled findings from 3 continents.

21 January 2018

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Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

21 January 2018

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Retinal age pigments generated by self-assembling lysosomotropic detergents

21 January 2018

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Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25378587

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E14-05-1028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378587%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25378587%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference