Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease (Q38315736)

2 September 2017

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease (English)

1 reference

2 September 2017

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1

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9 June 2020

Bernadette Carroll

2

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9 June 2020

Alex H M Ng

5

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9 June 2020

Malkiel A Cohen

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9 June 2020

Viktor Korolchuk

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9 June 2020

14

Rudolf Jaenisch

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9 June 2020

11

Hidde Ploegh

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9 June 2020

10

Eric Spooner

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9 June 2020

3

Yosef Buganim

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9 June 2020

author name string

Dorothea Maetzel

4

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9 June 2020

John P Cassady

6

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9 June 2020

Souvik Chakraborty

8

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9 June 2020

Haoyi Wang

9

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9 June 2020

Joerg Gsponer

12

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9 June 2020

publication date

27 November 2013

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2 September 2017

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9 June 2020

volume

5

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9 June 2020

issue

5

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9 June 2020

page(s)

1302-1315

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describes a project that uses

9 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3957429/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.

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6 September 2017

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Proteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain

6 September 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy

6 September 2017

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Autophagy modulation as a potential therapeutic target for diverse diseases

6 September 2017

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Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease

6 September 2017

1 reference

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Autophagy in lysosomal storage disorders

6 September 2017

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mTOR signaling in growth control and disease

6 September 2017

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Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice

6 September 2017

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6 September 2017

Mechanisms of mitophagy

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Regulation of mammalian autophagy in physiology and pathophysiology.

6 September 2017

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DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

6 September 2017

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Niemann‐Pick type C disease: molecular mechanisms and potential therapeutic approaches

6 September 2017

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Altered lipid content inhibits autophagic vesicular fusion

6 September 2017

1 reference

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

6 September 2017

1 reference

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Roles of cholesterol in vesicle fusion and motion.

6 September 2017

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Rab GTPases as coordinators of vesicle traffic

6 September 2017

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

6 September 2017

1 reference

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Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells

6 September 2017

1 reference

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Autophagy regulates lipid metabolism

6 September 2017

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Autophagy fights disease through cellular self-digestion

6 September 2017

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Cellular cholesterol trafficking and compartmentalization

6 September 2017

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

6 September 2017

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6 September 2017

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

6 September 2017

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

6 September 2017

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

6 September 2017

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Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

6 September 2017

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Signalling and autophagy regulation in health, aging and disease

6 September 2017

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

6 September 2017

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

6 September 2017

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Lithium induces autophagy by inhibiting inositol monophosphatase

6 September 2017

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The role of autophagy during the early neonatal starvation period

6 September 2017

1 reference

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Role for Rab7 in maturation of late autophagic vacuoles

6 September 2017

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

6 September 2017

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

6 September 2017

1 reference

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

6 September 2017

1 reference

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Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

6 September 2017

1 reference

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Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

14 September 2017

1 reference

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Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network

27 September 2017

1 reference

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Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1

27 September 2017

1 reference

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Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis

23 June 2018

1 reference

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Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes

23 June 2018

1 reference

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Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

23 June 2018

1 reference

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TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

23 June 2018

1 reference

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Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells

31 August 2018

1 reference

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Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

31 August 2018

1 reference

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Rapamycin pre-treatment protects against apoptosis

31 August 2018

1 reference

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10.1016/J.CELREP.2013.10.042

31 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24290752%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24290752%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

24290752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24290752%20AND%20SRC:MED&resulttype=core&format=json