Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells (Q30637438)

11 September 2017

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells (English)

1 reference

11 September 2017

1 reference

1 reference

4

Wilko Weichert

0 references

Achim Aigner

7

object named as

Achim Aigner

1 reference

11 September 2017

Norman Ertych

1

1 reference

11 September 2017

Ailine Stolz

2

1 reference

11 September 2017

Albrecht Stenzinger

3

1 reference

11 September 2017

Silke Kaulfuß

5

1 reference

11 September 2017

Peter Burfeind

6

1 reference

11 September 2017

Linda Wordeman

8

1 reference

11 September 2017

Holger Bastians

9

1 reference

11 September 2017

29 June 2014

1 reference

11 September 2017

1 reference

11 September 2017

16

1 reference

11 September 2017

8

1 reference

11 September 2017

779-791

1 reference

A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Replication stress links structural and numerical cancer chromosomal instability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The cancer biology of whole-chromosome instability.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Chromosomal instability and aneuploidy in cancer: from yeast to man

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Cancer chromosomal instability: therapeutic and diagnostic challenges

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Causes and consequences of aneuploidy in cancer.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The aneuploidy paradox: costs and benefits of an incorrect karyotype

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Merotelic kinetochore attachment: causes and effects.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Shared and separate functions of polo-like kinases and aurora kinases in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Tumor suppressor CHK2: regulator of DNA damage response and mediator of chromosomal stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Mechanisms of chromosomal instability.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Molecular origins of cancer: Molecular basis of colorectal cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Deviant kinetochore microtubule dynamics underlie chromosomal instability.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

A mechanism linking extra centrosomes to chromosomal instability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

XMAP215 is a processive microtubule polymerase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The genomic landscapes of human breast and colorectal cancers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Effects of aneuploidy on cellular physiology and cell division in haploid yeast

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Polo-like kinase 1 expression is a prognostic factor in human colon cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Microtubules as a target for anticancer drugs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Aurora B regulates MCAK at the mitotic centromere

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Centrosome maturation: measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Merotelic kinetochore orientation occurs frequently during early mitosis in mammalian tissue cells and error correction is achieved by two different mechanisms

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

The significance of unstable chromosomes in colorectal cancer.

14 July 2018

1 reference

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

21 January 2018

1 reference

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

21 January 2018

1 reference

The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

21 January 2018

1 reference

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics

21 January 2018

1 reference

Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis.

21 January 2018

1 reference

Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4389786

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24976383

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24976383

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB2994

1 reference

Dimensions Publication ID

11 September 2017

0 references

1 reference

11 September 2017

PubMed publication ID

24976383

1 reference