Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. (Q30652695)

25 June 2017

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. (English)

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25 June 2017

8

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25 June 2017

T Obata

1

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25 June 2017

M B Yaffe

2

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25 June 2017

G G Leparc

3

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25 June 2017

E T Piro

4

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25 June 2017

H Maegawa

5

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25 June 2017

A Kashiwagi

6

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25 June 2017

R Kikkawa

7

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25 June 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

25 June 2017

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25 June 2017

275

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25 June 2017

36108-36115

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25 June 2017

46

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Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

25 June 2017

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Thymic lymphoma induction by the AKT8 murine retrovirus

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

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Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

21 January 2018

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Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.

21 January 2018

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Interleukin 3-dependent survival by the Akt protein kinase

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Cellular survival: a play in three Akts

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Involvement of the pleckstrin homology domain in the insulin-stimulated activation of protein kinase B.

21 January 2018

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AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

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A phosphoinositide-binding sequence is shared by PH domain target molecules--a model for the binding of PH domains to proteins

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

21 January 2018

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Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

21 January 2018

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

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Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

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Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells

21 January 2018

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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Determination of the specific substrate sequence motifs of protein kinase C isozymes

21 January 2018

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Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

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MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

21 January 2018

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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

21 January 2018

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PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis

21 January 2018

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Pseudosubstrate-based peptide inhibitors

21 January 2018

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

21 January 2018

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

21 January 2018

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SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

21 January 2018

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The structural basis for 14-3-3:phosphopeptide binding specificity

21 January 2018

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RNA recognition by RNP proteins during RNA processing.

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ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

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Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

21 January 2018

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Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells

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Grabbing phosphoproteins

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A Bad kinase makes good

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005497200

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25 June 2017

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