Involvement of the pleckstrin homology domain in the insulin-stimulated activation of protein kinase B. (Q40999183)

25 September 2017

Involvement of the pleckstrin homology domain in the insulin-stimulated activation of protein kinase B. (English)

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25 September 2017

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4

Hemmings BA

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25 September 2017

Sable CL

1

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25 September 2017

Filippa N

series ordinal

2

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25 September 2017

Filloux C

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3

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25 September 2017

Van Obberghen E

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5

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25 September 2017

language of work or name

English

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publication date

1 November 1998

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Journal of Biological Chemistry

25 September 2017

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25 September 2017

273

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25 September 2017

45

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25 September 2017

29600-29606

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Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

25 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

D-3 phosphoinositide metabolism in cells treated with platelet-derived growth factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Regulatory recruitment of signalling molecules to the cell membrane by pleckstrinhomology domains.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Role of translocation in the activation and function of protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Protein kinase B and rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29600

21 January 2018

Identifiers

DOI

10.1074/JBC.273.45.29600

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25 September 2017

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