The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics (Q30699664)

26 June 2017

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title

The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics (English)

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26 June 2017

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Lorens JB

1

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26 June 2017

Sousa C

2

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26 June 2017

Bennett MK

3

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26 June 2017

Molineaux SM

4

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26 June 2017

Payan DG

5

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26 June 2017

publication date

1 December 2001

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Current Opinion in Biotechnology

26 June 2017

published in

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26 June 2017

volume

12

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26 June 2017

issue

6

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26 June 2017

page(s)

613-621

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New experimental approaches in retrovirus-mediated expression screening

26 June 2017

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Dominant effector genetics in mammalian cells

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Retroviral delivery of peptide modulators of cellular functions

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Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA

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DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

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Changing T cell specificity by retroviral T cell receptor display

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Dissociation of the high density lipoprotein and low density lipoprotein binding activities of murine scavenger receptor class B type I (mSR-BI) using retrovirus library-based activity dissection

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Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains

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7 January 2021

Identification of p53 genetic suppressor elements which confer resistance to cisplatin

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Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model

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Directed evolution of proteins by exon shuffling

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Molecular breeding of viruses

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Breeding of retroviruses by DNA shuffling for improved stability and processing yields

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Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex

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7 January 2021

Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria

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CD150 (SLAM) is a receptor for measles virus but is not involved in viral contact-mediated proliferation inhibition

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Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses

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The RD114/simian type D retrovirus receptor is a neutral amino acid transporter

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p53-independent role of MDM2 in TGF-beta1 resistance

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7 January 2021

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

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7 January 2021

Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

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7 January 2021

A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation

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7 January 2021

Identification of two short internal ribosome entry sites selected from libraries of random oligonucleotides

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7 January 2021

A novel artificial loop scaffold for the noncovalent constraint of peptides

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7 January 2021

Functional screening of a retroviral peptide library for MHC class I presentation

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7 January 2021

In vivo selection of protease cleavage sites from retrovirus display libraries

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7 January 2021

Complementation of Myc-dependent cell proliferation by cDNA expression library screening

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7 January 2021

Functional cloning of the proto-oncogene brain factor-1 (BF-1) as a Smad-binding antagonist of transforming growth factor-beta signaling

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7 January 2021

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7 January 2021

Establishment of okadaic acid resistant cell clones using a cDNA expression library

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7 January 2021

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7 January 2021

A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin

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7 January 2021

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Identifiers

DOI

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26 June 2017

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