Exploring the native human antibody repertoire to create antiviral therapeutics (Q30835752)

27 June 2017

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title

Exploring the native human antibody repertoire to create antiviral therapeutics (English)

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27 June 2017

Exploring the Native Human Antibody Repertoire to Create Antiviral Therapeutics (English)

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author name string

S K Dessain

1

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27 June 2017

S P Adekar

2

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27 June 2017

J D Berry

3

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27 June 2017

Scott K. Dessain

1

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S. P. Adekar

2

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J. D. Berry

3

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publication date

1 January 2008

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Current Topics in Microbiology and Immunology

27 June 2017

2008

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published in

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27 June 2017

317

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27 June 2017

155-183

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High efficiency creation of human monoclonal antibody-producing hybridomas

27 June 2017

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12 December 2020

Late cytomegalovirus disease and mortality in recipients of allogeneic hematopoietic stem cell transplants: importance of viral load and T-cell immunity

1 reference

12 December 2020

Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997.

1 reference

12 December 2020

Characterization of human monoclonal antibodies directed against hepatitis B surface antigen

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12 December 2020

Parvovirus B19 infection-related complications in renal transplant recipients: treatment with intravenous immunoglobulin

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12 December 2020

Generation of human monoclonal antibodies reactive with human mammary carcinoma cells

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12 December 2020

Comparative phenotypic analysis of available human hybridoma fusion partners

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12 December 2020

The selection and characterization of human monoclonal antibodies to human cytomegalovirus

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12 December 2020

Increased frequency of both total and specific monoclonal antibody producing hybridomas using a fusion partner that constitutively expresses recombinant IL-6.

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12 December 2020

Intravenous immunoglobulin products contain neutralizing antibodies to vaccinia

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12 December 2020

Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease

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12 December 2020

A randomized trial of high dose polyvalent intravenous immunoglobulin (HDIgG) vs. Cytomegalovirus (CMV) hyperimmune IgG in allogeneic hemopoietic stem cell transplants (HSCT)

1 reference

12 December 2020

Respiratory syncytial virus (RSV) immune globulin intravenous therapy for RSV lower respiratory tract infection in infants and young children at high risk for severe RSV infections: Respiratory Syncytial Virus Immune Globulin Study Group

1 reference

12 December 2020

Telomeres, chromosome instability and cancer

1 reference

12 December 2020

Characteristics of human antibody repertoires following active immune responses in vivo

1 reference

12 December 2020

Respiratory syncytial virus and other respiratory viruses

1 reference

12 December 2020

A microengraving method for rapid selection of single cells producing antigen-specific antibodies

1 reference

12 December 2020

A human monoclonal IgG1 lambda anti-hepatitis B surface antibody. Production, properties, and applications

1 reference

12 December 2020

Construction of human monoclonal antibodies against rabies NS-protein antigen by Epstein-Barr virus transformation

1 reference

12 December 2020

Development of a potent respiratory syncytial virus-specific monoclonal antibody for the prevention of serious lower respiratory tract disease in infants

1 reference

12 December 2020

Human monoclonal antibodies neutralizing varicella-zoster virus

1 reference

12 December 2020

Recommendations for protection against viral hepatitis

1 reference

12 December 2020

Hepatitis B in liver transplant recipients.

1 reference

12 December 2020

Generation of human monoclonal antibodies reactive with cellular antigens

1 reference

12 December 2020

Development of a fusion partner cell line for efficient production of human monoclonal antibodies from peripheral blood lymphocytes

1 reference

12 December 2020

Non-random human chromosome distribution in human-mouse myeloma somatic cell hybrids

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12 December 2020

Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries

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12 December 2020

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

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12 December 2020

Use of cytomegalovirus immune globulin to prevent cytomegalovirus disease in renal-transplant recipients

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12 December 2020

Antibody producing human-human hybridomas. I. Technical aspects

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12 December 2020

Mouse x human heterohybridomas as fusion partners with human B cell tumors

1 reference

12 December 2020

Human monoclonal antibodies to human cytomegalovirus derived from peripheral blood lymphocytes of healthy adults

1 reference

12 December 2020

Efficient preparation of human monoclonal antibody-secreting heterohybridomas using peripheral B lymphocytes cultured in the CD40 system.

1 reference

12 December 2020

Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus

1 reference

12 December 2020

Efficient production of IgG human monoclonal antibodies by lymphocytes stimulated by lipopolysaccharide, pokeweed mitogen, and interleukin 4

1 reference

12 December 2020

Long-term results of CMV hyperimmune globulin prophylaxis in 377 heart transplant recipients.

1 reference

12 December 2020

Rescue, expression, and analysis of a neutralizing human anti-hepatitis A virus monoclonal antibody.

1 reference

12 December 2020

Phase I study of safety and pharmacokinetics of a human anticytomegalovirus monoclonal antibody in allogeneic bone marrow transplant recipients

1 reference

12 December 2020

Respiratory syncytial virus immune globulin treatment of lower respiratory tract infection in pediatric patients undergoing bone marrow transplantation - a compassionate use experience

1 reference

12 December 2020

The development of monoclonal human rabies virus-neutralizing antibodies as a substitute for pooled human immune globulin in the prophylactic treatment of rabies virus exposure.

1 reference

12 December 2020

Prevention of varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP). Centers for Disease Control and Prevention

1 reference

12 December 2020

Increased human hybridoma formation by electrofusion of human B cells with heteromyeloma SPAM-8 cells

1 reference

12 December 2020

A human monoclonal antibody against varicella-zoster virus glycoprotein III

1 reference

12 December 2020

Limiting dilution analysis of Epstein-Barr virus-induced immunoglobulin production

1 reference

12 December 2020

Neutralizing human monoclonal antibodies to conformational epitopes of human T-cell lymphotropic virus type 1 and 2 gp46.

1 reference

12 December 2020

Preparation and characterization of human monoclonal antibodies directed against the hepatitis B virus surface antigen

1 reference

12 December 2020

Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates

1 reference

12 December 2020

Interleukin 6 and its receptor: ten years later

1 reference

12 December 2020

Passive antibody therapy for infectious diseases

1 reference

12 December 2020

Intravenous immunoglobulin: appropriate indications and uses in hematopoietic stem cell transplantation

1 reference

12 December 2020

Incidence and clinical consequences of surface and polymerase gene mutations in liver transplant recipients on hepatitis B immunoglobulin.

1 reference

12 December 2020

Prevention of hepatitis B virus carrier state in infants according to maternal serum levels of HBV DNA.

1 reference

12 December 2020

The potential of antibody-mediated immunity in the defence against biological weapons

1 reference

12 December 2020

A randomized controlled clinical trial: interruption of intrauterine transmission of hepatitis B virus infection with HBIG.

1 reference

12 December 2020

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

1 reference

12 December 2020

Generation of heterohybridomas secreting human immunoglobulins; pokeweed mitogen prestimulation is highly effective but phytohemagglutinin drives most B cells into apoptosis

1 reference

12 December 2020

Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface.

1 reference

12 December 2020

Antiviral drugs for cytomegalovirus diseases

1 reference

12 December 2020

Multiple pathways to cellular senescence: role of telomerase repressors

1 reference

12 December 2020

Neutralizing mechanisms of two human monoclonal antibodies against human cytomegalovirus glycoprotein 130/55

1 reference

12 December 2020

Complications of smallpox vaccination, 1968.

1 reference

12 December 2020

Prevention of cytomegalovirus infection and disease in high-risk renal transplant recipients with polyvalent intravenous immunoglobulins

1 reference

12 December 2020

Combined CMV Prophylaxis Improves Outcome and Reduces the Risk for Bronchiolitis Obliterans Syndrome (BOS) after Lung Transplantation

1 reference

12 December 2020

The construction and use of a human-mouse myeloma analogue suitable for the routine production of hybridomas secreting human monoclonal antibodies

1 reference

12 December 2020

Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells

1 reference

12 December 2020

A human monoclonal antibody cocktail as a novel component of rabies postexposure prophylaxis

1 reference

12 December 2020

A Rabies-Specific Human Monoclonal Antibody That Protects Mice Against Lethal Rabies

1 reference

12 December 2020

Understanding and making use of human memory B cells

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12 December 2020

Antibodies from phage antibody libraries

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12 December 2020

Hybrid somatic cells / Boris Ephrussi and Mary C. Weiss. - (1969)

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12 December 2020

Generation of neutralizing anti-B19 parvovirus human monoclonal antibodies from patients infected with human immunodeficiency virus

1 reference

12 December 2020

Hepatitis B immune globulin preparations and use in liver transplantation

1 reference

12 December 2020

Development and characterization of human anti-HBs antibodies

1 reference

12 December 2020

Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants

1 reference

12 December 2020

Human monoclonals from antigen-specific selection of B lymphocytes and transformation by EBV.

1 reference

12 December 2020

A new product (VariZIG) for postexposure prophylaxis of varicella available under an investigational new drug application expanded access protocol.

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12 December 2020

In vitro antiviral and antibacterial activity of commercial intravenous immunoglobulin preparations--a potential role for adjuvant intravenous immunoglobulin therapy in infectious diseases

1 reference

12 December 2020

Molecular characterization of human monoclonal antibodies derived from fusions of tonsil lymphocytes with a human myeloma cell line

1 reference

12 December 2020

Development of microfusion techniques to generate human hybridomas

1 reference

12 December 2020

Improved fusion partners transfected with DNA fragment encoding IL-11 on generation of human B lymphocyte hybridomas.

1 reference

12 December 2020

New display vector reduces biological bias for expression of antibodies in E. coli

1 reference

12 December 2020

Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis.

1 reference

12 December 2020

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

1 reference

12 December 2020

Increased proportion of B cell hybridomas secreting monoclonal antibodies of desired specificity in cultures containing macrophage-derived hybridoma growth factor (IL-6).

1 reference

12 December 2020

Telomerase upregulates expression levels of interleukin (IL)-1alpha, IL-1beta, IL-6, IL-8, and granulocyte-macrophage colony-stimulating factor in normal human fibroblasts

1 reference

12 December 2020

The outcome of congenital cytomegalovirus infection in relation to maternal antibody status

1 reference

12 December 2020

Preparation of human-mouse heterohybridomas against an immunising antigen

1 reference

12 December 2020

A human monoclonal antibody to cytomegalovirus (CMV)

1 reference

12 December 2020

Efficient immortalization of rheumatoid synovial tissue B-lymphocytes. A comparison between the techniques of electric field-induced and PEG fusion

1 reference

12 December 2020

Low-dose intramuscular hepatitis B immune globulin and lamivudine for long-term prophylaxis of hepatitis B recurrence after liver transplantation.

1 reference

12 December 2020

Reduction of respiratory syncytial virus hospitalization among premature infants and infants with bronchopulmonary dysplasia using respiratory syncytial virus immune globulin prophylaxis. The PREVENT Study Group

1 reference

12 December 2020

Establishment of hybridomas secreting human monoclonal antibodies against tetanus toxin and hepatitis B virus surface antigen

1 reference

12 December 2020

A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities

1 reference

12 December 2020

Postexposure prophylaxis of hepatitis B

1 reference

12 December 2020

The effects of hybridoma growth factor in conditioned media upon the growth, cloning, and antibody production of heterohybridoma cell lines

1 reference

12 December 2020

Delineation of optimal conditions for producing mouse-human heterohybridomas from human peripheral blood B cells of immunized subjects

1 reference

12 December 2020

Back to the future: antibody-based strategies for the treatment of infectious diseases

1 reference

12 December 2020

Passive immunity in prevention and treatment of infectious diseases

1 reference

12 December 2020

Recent advances in phage display

1 reference

12 December 2020

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

1 reference

12 December 2020

Murine bone marrow-derived macrophages constitute feeder cells for human B cell hybridomas

1 reference

12 December 2020

Biological characterization of human monoclonal antibodies to rabies virus

1 reference

12 December 2020

Parameters to enhance human hybridoma formation with hypoosmolar electrofusion

1 reference

12 December 2020

Immunoprophylaxis of infection with hepatitis B virus in infants born to hepatitis B surface antigen-positive carrier mothers

1 reference

12 December 2020

Characterization of human hybridomas secreting antibody to tetanus toxoid

1 reference

12 December 2020

Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP)

1 reference

12 December 2020

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

1 reference

12 December 2020

Human monoclonal antibodies specific for the rabies virus glycoprotein and N protein

1 reference

12 December 2020

Hybridomas producing human monoclonal antibodies against varicella-zoster virus

1 reference

12 December 2020

The high efficiency, human B cell immortalizing heteromyeloma CB-F7. Production of human monoclonal antibodies to human immunodeficiency virus

1 reference

12 December 2020

The generation of Ig-secreting UC 729-6 derived human hybridomas by electrofusion

1 reference

12 December 2020

Making antibodies by phage display technology

1 reference

12 December 2020

1 reference

12 December 2020

Isolation of native human monoclonal autoantibodies to breast cancer

1 reference

12 December 2020

Administration to mice of a monoclonal antibody that neutralizes the intracellular mature virus form of vaccinia virus limits virus replication efficiently under prophylactic and therapeutic conditions

1 reference

12 December 2020

SPAM-8, a mouse-human heteromyeloma fusion partner in the production of human monoclonal antibodies. Establishment of a human monoclonal antibody against cytomegalovirus.

1 reference

12 December 2020

Antibody neutralization of the extracellular enveloped form of vaccinia virus

1 reference

12 December 2020

Isolation of high affinity human antibodies directly from large synthetic repertoires.

1 reference

12 December 2020

Development of human monoclonal antibodies to rabies

1 reference

12 December 2020

Isolation of human antibody repertoires with preservation of the natural heavy and light chain pairing

1 reference

12 December 2020

High affinity human monoclonal antibodies directed against hepatitis B surface antigen

1 reference

12 December 2020

Human monoclonal antibodies produced by primary in vitro immunization of peripheral blood lymphocytes

1 reference

12 December 2020

Prevention of vertical hepatitis B transmission by hepatitis B immunoglobulin in the third trimester of pregnancy

1 reference

12 December 2020

MSL-109 adjuvant therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: the Monoclonal Antibody Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS Research Group. AIDS Clinical Trials Gro

1 reference

12 December 2020

Respiratory syncytial virus upper respiratory tract illnesses in adult blood and marrow transplant recipients: combination therapy with aerosolized ribavirin and intravenous immunoglobulin

1 reference

12 December 2020

Production of human hybridomas secreting antibodies to measles virus

1 reference

12 December 2020

Extensive loss of human DNA accompanies loss of antibody production in heteromyeloma hybridoma cells

1 reference

12 December 2020

Antiviral antibody responses: the two extremes of a wide spectrum

1 reference

12 December 2020

Growing human B lymphocytes in the CD40 system

1 reference

12 December 2020

Smallpox as a Biological Weapon

1 reference

12 December 2020

Anti-hepatitis B virus activity of a mixture of two monoclonal antibodies in an "inhibition in solution" assay

1 reference

12 December 2020

Structural characteristics of four human hybridoma antibodies specific for the pp65 protein of the human cytomegalovirus and their relationship to human rheumatoid factors.

1 reference

12 December 2020

Chickenpox in pregnancy: revisited

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12 December 2020

Pure red cell aplasia caused by Parvovirus B19 infection in solid organ transplant recipients: a case report and review of literature

1 reference

12 December 2020

Use of Epstein-Barr virus-transformed B cell lines for the generation of immunoglobulin-producing human B cell hybridomas

1 reference

12 December 2020

A human myeloma cell line suitable for the generation of human monoclonal antibodies

1 reference

12 December 2020

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

12 December 2020

Human monoclonal antibodies to human cytomegalovirus.

1 reference

12 December 2020

Parvovirus B19 in pregnancy

1 reference

12 December 2020

Production of human monoclonal IgG antibodies reacting with cytomegalovirus (CMV).

1 reference

12 December 2020

CD19+ B lymphocytes are the major source of human antibody-secreting hybridomas generated by electrofusion

1 reference

12 December 2020

Generation of neutralizing human monoclonal antibodies against parvovirus B19 proteins

1 reference

12 December 2020

Resistance to apoptosis in human cells conferred by telomerase function and telomere stability

1 reference

12 December 2020

A better cell line for making hybridomas secreting specific antibodies

1 reference

12 December 2020

Yeast surface display for screening combinatorial polypeptide libraries

1 reference

12 December 2020

Parvovirus B19 infection after transplantation: a review of 98 cases

1 reference

12 December 2020

Human anti-tetanus toxoid monoclonal antibody secreted by EBV-transformed human B cells fused with murine myeloma.

1 reference

12 December 2020

Genetic and immunological comparison of anti-botulinum type A antibodies from immune and non-immune human phage libraries

1 reference

12 December 2020

Cell hybridization, hybridomas, and human hybridomas

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12 December 2020

Hybrids from fusion of normal human T lymphocytes with immortal human cells exhibit limited life span

1 reference

12 December 2020

Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. The IMpact-RSV Study Group

1 reference

12 December 2020

Neutralizing murine monoclonal antibodies to human IL-5 isolated from hybridomas and a filamentous phage Fab display library

1 reference

12 December 2020

Comparing cytomegalovirus prophylaxis in renal transplantation: single center experience

1 reference

12 December 2020

Hepatitis B virus envelope variation after transplantation with and without hepatitis B immune globulin prophylaxis

1 reference

12 December 2020

Antibodies for the prevention and treatment of viral diseases

1 reference

12 December 2020

Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma

1 reference

12 December 2020

Probing the human antibody repertoire to exogenous antigens. Characterization of the H and L chain V region gene segments from anti-hepatitis B virus antibodies

1 reference

12 December 2020

Respiratory syncytial virus infection in elderly and high-risk adults

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12 December 2020

Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

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12 December 2020

HAB-1, a new heteromyeloma for continuous production of human monoclonal antibodies

1 reference

12 December 2020

Respiratory syncytial virus infection following hematopoietic stem cell transplantation

1 reference

12 December 2020

In vivo activity of a mixture of two human monoclonal antibodies (anti-HBs) in a chronic hepatitis B virus carrier chimpanzee

1 reference

12 December 2020

A human monoclonal antibody specific for the N terminus of the hepatitis C virus nucleocapsid protein.

1 reference

12 December 2020

Establishment of hybridoma secreting human monoclonal antibody against hepatitis B virus surface antigen

1 reference

12 December 2020

Spontaneous and radiation-induced genetic instability of heteromyeloma hybridoma cells

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12 December 2020

Combined passive and active immunoprophylaxis for preventing perinatal transmission of the hepatitis B virus in infants born to HBsAg positive mothers in comparison with vaccine alone

1 reference

12 December 2020

Immunoglobulin expression by human B lymphocytes clonally transformed by Epstein Barr virus

1 reference

12 December 2020

The formation and function of extracellular enveloped vaccinia virus

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12 December 2020

Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction.

1 reference

12 December 2020

Human monoclonal antibodies produced from L-leucine methyl ester-treated and in vitro immunized peripheral blood lymphocytes

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12 December 2020

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

12 December 2020

Low-dose hepatitis B immunoglobulin given "on demand" in combination with lamivudine: a highly cost-effective approach to prevent recurrent hepatitis B virus infection in the long-term follow-up after liver transplantation

1 reference

12 December 2020

Ocular vaccinia infection in laboratory worker, Philadelphia, 2004

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12 December 2020

Isolation and epitope characterization of human monoclonal antibodies to hepatitis C virus core antigen

1 reference

12 December 2020

A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines

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12 December 2020

Secretion capture and report web: use of affinity derivatized agarose microdroplets for the selection of hybridoma cells

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12 December 2020

A human hybrid hybridoma.

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12 December 2020

Risk factors for severe respiratory syncytial virus infection in infants.

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12 December 2020

Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

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12 December 2020

Clinical aspects of parvovirus B19 infection

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12 December 2020

Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies

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12 December 2020

Mortality associated with influenza and respiratory syncytial virus in the United States

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12 December 2020

Human monoclonal anti-D secreting heterohybridomas from peripheral B lymphocytes expanded in the CD40 system

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12 December 2020

Human chromosome 21 determines growth factor dependence in human/mouse B-cell hybridomas

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12 December 2020

Randomized, placebo-controlled, double-blind study of a cytomegalovirus-specific monoclonal antibody (MSL-109) for prevention of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation

1 reference

12 December 2020

10.1007/978-3-540-72146-8_6

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