Interleukin 6 and its receptor: ten years later (Q41722189)

8 October 2017

1 reference

title

Interleukin 6 and its receptor: ten years later (English)

1 reference

8 October 2017

Hirano T

1

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8 October 2017

1 January 1998

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International Reviews of Immunology

8 October 2017

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8 October 2017

16

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8 October 2017

3-4

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8 October 2017

249-284

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Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

8 October 2017

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Anti-beta-interferon antibodies inhibit the increased expression of HLA-B7 mRNA in tumor necrosis factor-treated human fibroblasts: structural studies of the beta 2 interferon involved

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin-6 and the acute phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Haemopoietic receptors and helical cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Structural design and molecular evolution of a cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Cytokine signaling through nonreceptor protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

IL-6 cytokine family and signal transduction: a model of the cytokine system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Molecular cloning and expression of an IL-6 signal transducer, gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

STATs: signal transducers and activators of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

IgG1 plasmacytosis in interleukin 6 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin 6 is essential for in vivo development of B lineage neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

The role of interleukin-6 in mucosal IgA antibody responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

LIF: lots of interesting functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Purification of a lipoprotein lipase-inhibiting protein produced by a melanoma cell line associated with cancer cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Purification of adult rat sciatic nerve ciliary neuronotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Generation of sensory neurons is stimulated by leukemia inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin M

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin 11.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Growth factor requirements for survival in G0 and entry into the cell cycle of primitive human hemopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Neuronal differentiation factors/cytokines and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Characterization of a multicomponent receptor for GDNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin-6-induced tyrosine phosphorylation of multiple proteins in murine hematopoietic lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Transcriptional activation of the IL-6 response element in the junB promoter is mediated by multiple Stat family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification of a novel interleukin-6 response element containing an Ets-binding site and a CRE-like site in the junB promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Requirement of serine phosphorylation for formation of STAT-promoter complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Essential role of Stat6 in IL-4 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Identification of a Stat gene that functions in Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

An interleukin-4-induced transcription factor: IL-4 Stat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Mycobacteria and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Pathologic conditions associated with plasma cell dyscrasias: a study of 806 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Slow bacterial infections or autoimmunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Enhanced production of interleukin-6 in mice with type II collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

In vitro regulation of B cell differentiation by interleukin-6 and soluble CD23 in systemic lupus erythematosus B cell subpopulations and antigen-induced normal B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

A new view of the beta cell as an antigen-presenting cell and immunogenic target

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin-6 and its relation to inflammation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Interleukin 6 and autoimmunity and plasma cell neoplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Detection of a human intracisternal A-type retroviral particle antigenically related to HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Induction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Transcriptional activation of the interleukin-6 gene by HTLV-1 p40tax through an NF-kappa B-like binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Endogenous RNA tumor viruses are activated during chemical induction of murine plasmacytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

The role of oil and agalactosyl IgG in the induction of arthritis in rodent models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809042997

10.3109/08830189809042997

21 January 2018

Identifiers

DOI

1 reference

8 October 2017

1 reference

PubMed ID

9505191