Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial (Q30836702)

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English	Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial	scientific article

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16 October 2017

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial (English)

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16 October 2017

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Michael Platten

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Stefan M. Pfister

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Volker Hovestadt

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Michael Weller

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Wolfgang Wick

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Guido Reifenberger

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Guido Reifenberger

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David Capper

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Richard Meyermann

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Richard Meyermann

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Martin Sill

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David T. W. Jones

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David T W Jones

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ORCID Public Data File 2021

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Otmar D Wiestler

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Kathy Keyvani

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Joerg Felsberg

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Christian Hartmann

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Wolfgang Feiden

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Thorsten Pietsch

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15 July 2014

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1630-1638

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16 October 2017

Neuro-oncology in 2013: improving outcome in newly diagnosed malignant glioma

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ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

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Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of

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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

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21 June 2018

IDH testing in diagnostic neuropathology: review and practical guideline article invited by the Euro-CNS research committee

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21 June 2018

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

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A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.

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Gone FISHing: clinical lessons learned in brain tumor molecular diagnostics over the last decade

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

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21 June 2018

MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.

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Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

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IDH1 and IDH2 mutations in gliomas

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Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.

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Long-term survival with glioblastoma multiforme

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All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

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NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

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Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation

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Allelic status of 1p and 19q in oligodendrogliomas and glioblastomas: multiplex ligation-dependent probe amplification versus loss of heterozygosity

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Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

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25 November 2018

Identifiers

10.1093/NEUONC/NOU138

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Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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