Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis (Q30859046)

18 August 2017

Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis (English)

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18 August 2017

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11

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Steven B Bradfute

3

object named as

Steven B Bradfute

1 reference

18 August 2017

Rekha G Panchal

1

1 reference

18 August 2017

Ricky L Ulrich

2

1 reference

18 August 2017

Douglas Lane

4

1 reference

18 August 2017

Gordon Ruthel

5

1 reference

18 August 2017

Tara A Kenny

6

1 reference

18 August 2017

Patrick L Iversen

7

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18 August 2017

Arthur O Anderson

8

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18 August 2017

Rick Gussio

9

1 reference

18 August 2017

William C Raschke

10

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18 August 2017

language of work or name

English

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publication date

6 March 2009

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Journal of Biological Chemistry

18 August 2017

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18 August 2017

284

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18 August 2017

19

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18 August 2017

12874-12885

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Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Interferon protects mice against inhalation anthrax

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Evidence against a human cell-specific role for LRP6 in anthrax toxin entry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Manipulation of host-cell pathways by bacterial pathogens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Why is there so much CD45 on T cells?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Chemical genetic screening identifies critical pathways in anthrax lethal toxin-induced pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Cutting Edge: IFN-gamma-producing CD4 T lymphocytes mediate spore-induced immunity to capsulated Bacillus anthracis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Polyvalent inhibitors of anthrax toxin that target host receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Anthrax lethal toxin impairs innate immune functions of alveolar macrophages and facilitates Bacillus anthracis survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Targeting the PTPome in human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Inhibitors of protein tyrosine phosphatases: next-generation drugs?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Dual specificity protein phosphatases: therapeutic targets for cancer and Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Anthrax lethal toxin: a weapon of multisystem destruction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Cytokine response to infection with Bacillus anthracis spores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Murine model of pulmonary anthrax: kinetics of dissemination, histopathology, and mouse strain susceptibility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Protein tyrosine phosphatases in the human genome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Molecular design and biological activities of protein-tyrosine phosphatase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Small Molecule Regulation of Phosphatase-Dependent Cell Signaling Pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

CD45: a critical regulator of signaling thresholds in immune cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Low-molecular-weight protein tyrosine phosphatase and human disease: in search of biochemical mechanisms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Exploitation of host cell signaling machinery: activation of macrophage phosphotyrosine phosphatases as a novel mechanism of molecular microbial pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Role of toxin functional domains in anthrax pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Positive and negative regulation of Src-family membrane kinases by CD45.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Proteasome activity is required for anthrax lethal toxin to kill macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Morpholino antisense oligomers: design, preparation, and properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Exploitation of mammalian host cell functions by bacterial pathogens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Characterization of macrophage sensitivity and resistance to anthrax lethal toxin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Leukocyte common antigen (CD45) is required for immunoglobulin E-mediated degranulation of mast cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

CD45-cross-linking stimulates IFN-gamma production in NK cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Internalization and processing of Bacillus anthracis lethal toxin by toxin-sensitive and -resistant cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676018

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

The role of intron sequences in high level expression from CD45 cDNA constructs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

A CD45 minigene restores regulated isoform expression and immune function in CD45-deficient mice: therapeutic implications for human CD45-null severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

Effects of the protein tyrosine phosphatase CD45 on FcgammaRIIa signaling and neutrophil function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

Potent reversible inhibitors of the protein tyrosine phosphatase CD45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M809633200

CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19269962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CD45 is required for type I IFN production by dendritic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19269962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M809633200

1 reference

18 August 2017

1 reference

18 August 2017

1 reference