A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation (Q30865851)

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English	A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation	scientific article

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scholarly article

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Europe PubMed Central

27 June 2017

A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation (English)

1 reference

Europe PubMed Central

27 June 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

10

object named as

Amira Klip

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Europe PubMed Central

27 June 2017

Philipp E. Scherer

8

object named as

Philipp E Scherer

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Europe PubMed Central

27 June 2017

author name string

Romel Somwar

1

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Europe PubMed Central

27 June 2017

Sandra Koterski

2

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Europe PubMed Central

27 June 2017

Gary Sweeney

3

1 reference

Europe PubMed Central

27 June 2017

Richard Sciotti

4

1 reference

Europe PubMed Central

27 June 2017

Stevan Djuric

5

1 reference

Europe PubMed Central

27 June 2017

Cathy Berg

6

1 reference

Europe PubMed Central

27 June 2017

James Trevillyan

7

1 reference

Europe PubMed Central

27 June 2017

Christina M Rondinone

9

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Europe PubMed Central

27 June 2017

language of work or name

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publication date

21 October 2002

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Europe PubMed Central

27 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

27 June 2017

277

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Europe PubMed Central

27 June 2017

52

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Europe PubMed Central

27 June 2017

50386-50395

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Europe PubMed Central

27 June 2017

The search for physiological substrates of MAP and SAP kinases in mammalian cells

1 reference

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

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p38-2, a novel mitogen-activated protein kinase with distinct properties.

1 reference

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

1 reference

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The primary structure of p38 gamma: a new member of p38 group of MAP kinases

1 reference

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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

1 reference

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21 January 2018

Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

1 reference

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Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines

1 reference

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21 January 2018

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

1 reference

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21 January 2018

The p38 signal transduction pathway: activation and function

1 reference

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21 January 2018

An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase

1 reference

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21 January 2018

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

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21 January 2018

MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

1 reference

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The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells

1 reference

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21 January 2018

Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1

1 reference

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21 January 2018

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase

1 reference

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21 January 2018

Evidence of two mechanisms for the activation of the glucose transporter GLUT1 by anisomycin: p38(MAP kinase) activation and protein synthesis inhibition in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Dissection of stress-activated glucose transport from insulin-induced glucose transport in mammalian cells using wortmannin and ML-9.

1 reference

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21 January 2018

MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Cloning of a Rab3 isotype predominantly expressed in adipocytes

1 reference

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21 January 2018

Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

1 reference

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21 January 2018

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

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21 January 2018

The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway

1 reference

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21 January 2018

Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway.

1 reference

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21 January 2018

GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay

1 reference

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21 January 2018

Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in l6 muscle cells

1 reference

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21 January 2018

Stimulation of glucose and amino acid transport and activation of the insulin signaling pathways by insulin lispro in L6 skeletal muscle cells

1 reference

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21 January 2018

Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580.

1 reference

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21 January 2018

Sustained exposure of L6 myotubes to high glucose and insulin decreases insulin-stimulated GLUT4 translocation but upregulates GLUT4 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205277200

21 January 2018

Inhibition by forskolin of insulin-stimulated glucose transport in L6 muscle cells

1 reference

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21 January 2018

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations

1 reference

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Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4

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Insulin-responsive aminopeptidase trafficking in 3T3-L1 adipocytes

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Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle

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Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance

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Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation

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Qualitative and quantitative comparison of glucose transport activity and glucose transporter concentration in plasma membranes from basal and insulin-stimulated rat adipose cells

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Determination of the rates of appearance and loss of glucose transporters at the cell surface of rat adipose cells

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Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus

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Identification of wortmannin-sensitive targets in 3T3-L1 adipocytes. DissociationoOf insulin-stimulated glucose uptake and glut4 translocation.

1 reference

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Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway

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Antiapoptotic signaling by the insulin receptor in Chinese hamster ovary cells.

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Recruitment of GLUT-4 glucose transporters by insulin in diabetic rat skeletal muscle

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Insulin action on whole body glucose utilization and on muscle glucose transporter translocation in mice.

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Glucose transport and GLUT4 protein distribution in skeletal muscle of GLUT4 transgenic mice

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Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

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Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice

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Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport

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High-Fat Feeding Impairs Insulin-Stimulated GLUT4 Recruitment via an Early Insulin-Signaling Defect

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M205277200

1 reference

Europe PubMed Central

27 June 2017

1 reference

Europe PubMed Central

27 June 2017

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