Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques. (Q30974615)

27 June 2017

Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

1 reference

A Mukherjee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

E Song

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

M Kihiko-Ehmann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

J P Goodman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

J S Pyrek

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

S Estus

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

L B Hersh

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 December 2000

1 reference

27 June 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

page(s)

8745-8749

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger.

12 May 2020

cites work

1 reference

12 December 2020

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

12 December 2020

Alzheimer's disease: a central role for amyloid

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations.

1 reference

12 December 2020

Deposition of soluble amyloid-beta onto amyloid templates: with application for the identification of amyloid fibril extension inhibitors.

1 reference

12 December 2020

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

1 reference

12 December 2020

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

12 December 2020

Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils

1 reference

12 December 2020

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

1 reference

12 December 2020

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

1 reference

12 December 2020

Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

1 reference

12 December 2020

Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism

1 reference

12 December 2020

Selective inhibition of Abeta fibril formation

1 reference

12 December 2020

A beta deposition inhibitor screen using synthetic amyloid.

1 reference

12 December 2020

Identification of gamma-endorphin-generating enzyme as insulin-degrading enzyme

1 reference

12 December 2020

The plasmin system is induced by and degrades amyloid-beta aggregates

1 reference

12 December 2020

Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.

1 reference

12 December 2020

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

1 reference

12 December 2020

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

1 reference

12 December 2020

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

1 reference

12 December 2020

Labeling of cerebral amyloid in vivo with a monoclonal antibody.

1 reference

12 December 2020

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease

1 reference

12 December 2020

Arrest of beta-amyloid fibril formation by a pentapeptide ligand

1 reference

12 December 2020

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

1 reference

12 December 2020

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

1 reference

12 December 2020

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

1 reference

12 December 2020

10.1523/JNEUROSCI.20-23-08745.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6773064&resulttype=core&format=json

12 May 2020

1 reference