High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells. (Q30988504)

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6 November 2019

title

High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells (English)

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6 November 2019

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3

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6 November 2019

author name string

T A Sohn

1

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6 November 2019

G H Su

2

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6 November 2019

C J Yeo

4

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6 November 2019

S E Kern

5

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language of work or name

English

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publication date

1 May 2001

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6 November 2019

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6 November 2019

volume

233

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6 November 2019

issue

5

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6 November 2019

page(s)

696-703

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

6 November 2019

cites work

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12 December 2020

TGF-beta receptor signaling

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12 December 2020

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

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12 December 2020

A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library.

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12 December 2020

Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

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12 December 2020

Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas

1 reference

12 December 2020

Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease

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12 December 2020

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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12 December 2020

DPC4 gene in various tumor types

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12 December 2020

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

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12 December 2020

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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12 December 2020

Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

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12 December 2020

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

1 reference

12 December 2020

Characterization of functional domains within Smad4/DPC4

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12 December 2020

Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells

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12 December 2020

Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-beta through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway

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12 December 2020

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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12 December 2020

Mutations of the DPC4/Smad4 gene in biliary tract carcinoma.

1 reference

12 December 2020

Mads and Smads in TGF beta signalling

1 reference

12 December 2020

Smads and early developmental signaling by the TGFbeta superfamily

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12 December 2020

Dpc4 transcriptional activation and dysfunction in cancer cells.

1 reference

12 December 2020

Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.

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12 December 2020

G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation

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12 December 2020

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

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12 December 2020

Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

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12 December 2020

10.1097/00000658-200105000-00014

Identifiers

DOI

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