Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis (Q30994355)

2 October 2017

Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis (English)

1 reference

2 October 2017

1 reference

Fei Zhu

1

1 reference

2 October 2017

Pu Wang

2

1 reference

2 October 2017

Norman H Lee

3

1 reference

2 October 2017

Mary B Goldring

4

1 reference

2 October 2017

Konstantinos Konstantopoulos

5

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2 October 2017

language of work or name

English

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publication date

29 December 2010

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2 October 2017

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2 October 2017

5

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2 October 2017

12

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2 October 2017

e15174

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Creative Commons Attribution 4.0 International

2 October 2017

start time

29 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

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Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis

21 June 2018

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Comparable response of ccn1 with ccn2 genes upon arthritis: An in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines

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Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts

21 June 2018

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Culture of immortalized chondrocytes and their use as models of chondrocyte function

21 June 2018

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DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway

21 June 2018

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Modelling cartilage mechanobiology

21 June 2018

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CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear

21 June 2018

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Shear-induced cyclooxygenase-2 via a JNK2/c-Jun-dependent pathway regulates prostaglandin receptor expression in chondrocytic cells

21 June 2018

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21 June 2018

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COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells

21 June 2018

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Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts

21 June 2018

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Apoptotic chondrocyte death in human osteoarthritis.

21 June 2018

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21 June 2018

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Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

21 June 2018

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Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

21 June 2018

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Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

21 June 2018

1 reference

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Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes

21 June 2018

1 reference

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Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

21 June 2018

1 reference

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Increase of RhoB in gamma-radiation-induced apoptosis is regulated by c-Jun N-terminal kinase in Jurkat T cells.

25 November 2018

1 reference

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A critical role of Cyr61 in interleukin-17-dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis

25 November 2018

1 reference

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

25 November 2018

1 reference

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The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease

25 November 2018

1 reference

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Hyaluronan-binding receptors: possible involvement in osteoarthritis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Transcriptional activity of the RHOB gene is influenced by regulatory polymorphisms in its promoter region

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPbeta-dependent pathway

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Plasma level of CXC-chemokine CXCL12 is increased in rheumatoid arthritis and is independent of disease activity and methotrexate treatment.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Post-traumatic osteoarthritis: the role of stress induced chondrocyte damage.

25 November 2018

1 reference

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Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Microarray analysis of differential gene expression in temporomandibular joint condylar cartilage after experimentally induced osteoarthritis.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Seasonal episodic paroxysmal hemicrania responding to cyclooxygenase-2 inhibitors

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Regulation of nitric oxide and bcl-2 expression by shear stress in human osteoarthritic chondrocytes in vitro

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Proteasomal degradation of oxidatively damaged endogenous histones in K562 human leukemic cells

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Immunohistochemical localization of metallothionein in synovial tissue of patients with chronic inflammatory and degenerative joint disease.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012157

Global analyses of gene expression in early experimental osteoarthritis

25 November 2018

1 reference

12 December 2020

Expression of interleukin-6 in osteoarthritic chondrocytes and effects of fluid-induced shear on this expression in normal human chondrocytes in vitro

1 reference

12 December 2020

Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage

1 reference

12 December 2020

Suppression of collagen-induced arthritis with histone H1

1 reference

12 December 2020

Involvement of poly(ADP-ribose) polymerase 1 in ERBB2 expression in rheumatoid synovial cells

1 reference

12 December 2020

Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis

1 reference

12 December 2020

Effects of shear stress on nitric oxide and matrix protein gene expression in human osteoarthritic chondrocytes in vitro

1 reference

12 December 2020

Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc

1 reference

12 December 2020

Upregulation of urokinase-type plasminogen activator and inhibitor and gelatinase expression via 3 mitogen-activated protein kinases and PI3K pathways during the early development of osteoarthritis

1 reference

12 December 2020

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

1 reference

12 December 2020

Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0015174

Identifiers

DOI

1 reference

2 October 2017

0 references

1 reference

2 October 2017

PubMed publication ID

21209926

1 reference