A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth. (Q31099877)

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11 November 2019

title

A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth (English)

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11 November 2019

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3

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4

Stanley J Korsmeyer

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11 November 2019

author name string

Valeria R Fantin

series ordinal

1

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Marcelo J Berardi

series ordinal

2

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11 November 2019

Philip Leder

series ordinal

5

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11 November 2019

publication date

1 July 2002

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11 November 2019

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11 November 2019

volume

2

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issue

1

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page(s)

29-42

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describes a project that uses

11 November 2019

Eph4 A6

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cites work

Cytotoxic effect of thiacarbocyanine dyes on human colon carcinoma cells and inhibition of bovine heart mitochondrial NADH-ubiquinone reductase activity via a rotenone-type mechanism by two of the dyes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Phase I and II clinical trials of trastuzumab

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Mitochondria and cell death. Mechanistic aspects and methodological issues

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Mitochondria exert a negative feedback on the propagation of intracellular Ca2+ waves in rat cortical astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Mitochondrion as a novel target of anticancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Oncogenic alterations of metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The role of a mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particles

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Ethyl-nitrosourea transformed astrocytes exhibit mitochondrial membrane hyperpolarization and constrained apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Active cell membrane mechanisms involved in the exclusion of Rh 123 allow distinction between normal and tumoral cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The role of overexpressed HER2 in transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: role as anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Phase I trial of the selective mitochondrial toxin MKT 077 in chemo-resistant solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Mitochondria, oxygen free radicals, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

The basic biology of HER2.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

On the voltage dependence of the mitochondrial permeability transition pore. A critical appraisal.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Chloromethyltetramethylrosamine (Mitotracker Orange) induces the mitochondrial permeability transition and inhibits respiratory complex I. Implications for the mechanism of cytochrome c release.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Epidermal growth factor receptor as a target: recent developments in the search for effective new anti-cancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Tumor suppressor p53: regulation and function

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

New combinations with Herceptin in metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Biology of HER2 and its importance in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Revertants of v-fos-transformed fibroblasts have mutations in cellular genes essential for transformation by other oncogenes.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

Receptor tyrosine kinase signalling as a target for cancer intervention strategies

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900082-X

7 January 2021

10.1016/S1535-6108(02)00082-X

Identifiers

DOI

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11 November 2019

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