Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay (Q31105703)

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English	Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay	scientific article

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay (English)

1 reference

Europe PubMed Central

14 September 2017

Huntington's disease

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1 reference

based on heuristic

inferred from title

15

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Europe PubMed Central

14 September 2017

14

object named as

Hans Lehrach

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Europe PubMed Central

14 September 2017

Stephanie Waelter

6

object named as

Stephanie Waelter

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Europe PubMed Central

14 September 2017

Sabine Engemann

2

object named as

Sabine Engemann

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Europe PubMed Central

14 September 2017

8

object named as

Rudi Lurz

1 reference

Europe PubMed Central

14 September 2017

Annett Boeddrich

5

object named as

Annett Boeddrich

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Europe PubMed Central

14 September 2017

Nancy Schugardt

9

object named as

Nancy Schugardt

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Europe PubMed Central

14 September 2017

author name string

Volker Heiser

1

1 reference

Europe PubMed Central

14 September 2017

Wolfgang Bröcker

3

1 reference

Europe PubMed Central

14 September 2017

Ilona Dunkel

4

1 reference

Europe PubMed Central

14 September 2017

Eddi Nordhoff

7

1 reference

Europe PubMed Central

14 September 2017

Susanne Rautenberg

10

1 reference

Europe PubMed Central

14 September 2017

Christian Herhaus

11

1 reference

Europe PubMed Central

14 September 2017

Gerhard Barnickel

12

1 reference

Europe PubMed Central

14 September 2017

Henning Böttcher

13

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Europe PubMed Central

14 September 2017

language of work or name

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publication date

28 August 2002

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Europe PubMed Central

14 September 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

14 September 2017

99 Suppl 4

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Europe PubMed Central

14 September 2017

16400-16406

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Europe PubMed Central

14 September 2017

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Protein aggregation in Huntington's and Parkinson's disease: implications for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Riluzole therapy in Huntington's disease (HD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Chemical chaperones interfere with the formation of scrapie prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

21 June 2018

Identification of an HD patient with a (CAG)180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

2 references

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139900

25 November 2018

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Amyloid fibril formation in microwell plates for screening of inhibitors

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

A beta deposition inhibitor screen using synthetic amyloid.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182426599

21 January 2018

Riluzole series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12200548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/12200548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

https://pubmed.ncbi.nlm.nih.gov/12200548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.182426599

1 reference

Europe PubMed Central

14 September 2017

2002PNAS...9916400H

0 references

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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