Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria (Q31123008)

29 June 2017

Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria (English)

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29 June 2017

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7

Eskil Elmér

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29 June 2017

Magnus J Hansson

1

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Tadeusz Wieloch

object named as

Tadeusz Wieloch

series ordinal

6

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Hans Friberg

series ordinal

3

object named as

Hans Friberg

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29 June 2017

4

Marcus F Keep

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29 June 2017

Tanja Persson

2

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PubMed ID

12505662

29 June 2017

Anthony Rees

series ordinal

5

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PubMed ID

12505662

29 June 2017

language of work or name

English

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publication date

1 January 2003

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29 June 2017

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29 June 2017

960

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29 June 2017

1-2

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29 June 2017

99-111

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Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver.

29 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Immunosuppressant FK506 does not exert beneficial effects in symptomatic G93A superoxide dismutase-1 transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: relationship between pore opening and the activity of mitochondrial phospholipases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Postinjury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Action of cyclosporine on mitochondrial calcium fluxes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondria and apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The Ca2+ transport mechanisms of mitochondria and Ca2+ uptake from physiological-type Ca2+ transients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mechanisms by which mitochondria transport calcium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Regulation of the mitochondrial matrix volume in vivo and in vitro. The role of calcium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The Ca2+-induced membrane transition in mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Allosteric inhibition of the Ca2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

inferred from DOI database lookup

7 January 2021

based on heuristic

The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Intrathecal cyclosporin prolongs survival of late-stage ALS mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Biochemical characterization of the mitochondrial permeability transition in isolated forebrain mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: effect of cyclosporin A and ubiquinone O

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Calcium in ischemic cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The mitochondrial death/life regulator in apoptosis and necrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Effects of intracarotid arterial injection of cyclosporin A and spontaneous hypothermia on brain damage incurred after a long period of global ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A enhances survival, ameliorates brain damage, and prevents secondary mitochondrial dysfunction after a 30-minute period of transient cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondria buffer non-toxic calcium loads and release calcium through the mitochondrial permeability transition pore and sodium/calcium exchanger in rat basal forebrain neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondria in neurodegeneration: bioenergetic function in cell life and death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The role of creatine kinase in inhibition of mitochondrial permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Distinct Ca2+ thresholds determine cytochrome c release or permeability transition pore opening in brain mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cell damage in the brain: a speculative synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Brain mitochondrial responses to postischemic reperfusion: a role for calcium and hydrogen peroxide?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Glutamate-induced neuron death requires mitochondrial calcium uptake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The mitochondrial megachannel is the permeability transition pore

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The role of mitochondrial porins and the permeability transition pore in learning and synaptic plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

The mitochondrial permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Mitochondrial permeability transition in the central nervous system: induction by calcium cycling-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903798-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-8993(02)03798-8

1 reference

29 June 2017

1 reference

PubMed ID

12505662