Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin (Q31134336)

29 June 2017

Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin (English)

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29 June 2017

Patrik Onnerfjord

2

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Arnold Caplan

object named as

Arnold I Caplan

8

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author name string

David A Carrino

1

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29 June 2017

John D Sandy

3

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29 June 2017

Gabriella Cs-Szabo

4

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29 June 2017

Paul G Scott

5

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29 June 2017

J Michael Sorrell

6

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29 June 2017

Dick Heinegård

7

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29 June 2017

language of work or name

English

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publication date

5 March 2003

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Journal of Biological Chemistry

29 June 2017

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29 June 2017

278

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29 June 2017

19

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29 June 2017

17566-17572

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https://api.crossref.org/works/10.1074%2FJBC.M300124200

29 June 2017

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Age-dependent changes of hyaluronan in human skin

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Developmentally programmed expression of hyaluronan in human skin and its appendages

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Characterization of the skin in vivo by high resolution magnetic resonance imaging: water behavior and age-related effects

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Decorin interacts with fibrillar collagen of embryonic and adult human skin

21 January 2018

1 reference

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Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

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Non-proteoglycan forms of biglycan increase with age in human articular cartilage

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Glycation during human dermal intrinsic and actinic ageing: an in vivo and in vitro model study

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Patterns of Glycosaminoglycan/Proteoglycan Immunostaining in Human Skin During Aging

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Two species of dermatan sulfate proteoglycans with different molecular sizes from newborn calf skin

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Regulation of corneal collagen fibrillogenesis in vitro by corneal proteoglycan (lumican and decorin) core proteins

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1 reference

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The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23

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1 reference

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Human decorin gene: intron-exon junctions and chromosomal localization

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Decorin-binding sites for collagen type I are mainly located in leucine-rich repeats 4-5.

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Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen

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Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor

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Decorin is a biological ligand for the epidermal growth factor receptor

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Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope

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Articular cartilage and changes in arthritis: matrix degradation

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Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase

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Mechanisms involved in cartilage proteoglycan catabolism

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Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)

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Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4

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A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease?

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Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3

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Selective cleavage of human IgG by the matrix metalloproteinases, matrilysin and stromelysin

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The tumor necrosis factor-alpha converting enzyme (TACE): a unique metalloproteinase with highly defined substrate selectivity

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ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors

21 January 2018

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ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain

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Aging and cross-linking of skin collagen

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Human dermal glycosaminoglycans and aging

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Age and the chemical constitution of normal human dermis

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Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging

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Deficiency of the core proteins of dermatan sulphate proteoglycans in a variant form of Ehlers-Danlos syndrome

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The proteoglycans in hypertrophic scar

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Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar

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Characteristics and localization of rat submandibular gland proteoglycans

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Critical role of glutamate in a central leucine-rich repeat of decorin for interaction with type I collagen

21 January 2018

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An Anti-oncogenic Role for Decorin

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The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

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21 January 2018

Identifiers

DOI

10.1074/JBC.M300124200

1 reference

29 June 2017

1 reference