Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine (Q31381918)

1 July 2017

title

Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine (English)

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1 July 2017

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5

E De Clercq

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Jan Balzarini

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object named as

J Balzarini

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1 July 2017

C McGuigan

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L Bidois

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A Hiouni

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C Ballatore

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publication date

1 March 2000

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Antiviral Chemistry & Chemotherapy

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published in

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volume

11

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issue

2

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page(s)

111-116

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Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives

1 July 2017

cites work

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https://api.crossref.org/works/10.1177%2F095632020001100203

Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100203

Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT.

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100203

Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by-pass thymidine kinase

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100203

Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020001100203

Synthesis and evaluation of some masked phosphate esters of the anti-herpesvirus drug 882C (netivudine) as potential antiviral agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

Synthesis, anti-human immunodeficiency virus activity and esterase lability of some novel carboxylic ester-modified phosphoramidate derivatives of stavudine (d4T).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

Synthesis and anti-HIV activity of some novel chain-extended phosphoramidate derivatives of d4T (stavudine): esterase hydrolysis as a rapid predictive test for antiviral potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

Phosphoramidate derivatives of 2′,3′-didehydro-2′,3′-dideoxyadenosine [d4A] have markedly improved anti-HIV potency and selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020001100203

10.1177/095632020001100203

21 January 2018

Identifiers

DOI

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1 July 2017

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