Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by-pass thymidine kinase (Q41447739)

30 September 2017

title

Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by-pass thymidine kinase (English)

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30 September 2017

McGuigan C

1

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30 September 2017

Bellevergue P

2

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Sheeka H

3

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30 September 2017

Mahmood N

4

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30 September 2017

Hay AJ

5

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language of work or name

English

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publication date

1 August 1994

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30 September 2017

number of pages

4

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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volume

351

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issue

1

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page(s)

11-14

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

30 September 2017

cites work

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

21 January 2018

1 reference

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Synthesis and anti-HIV activity of some haloalkyl phosphoramidate derivatives of 3'-azido-3'-deoxythymidine (AZT): potent activity of the trichloroethyl methoxyalaninyl compound

21 January 2018

1 reference

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Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

21 January 2018

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Synthesis and biological properties of novel phosphotriesters: a new approach to the introduction of biologically active nucleotides into cells

21 January 2018

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Lipophilic glycosyl phosphotriester derivatives of AZT: synthesis, NMR transmembrane transport study, and antiviral activity

21 January 2018

1 reference

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3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents

21 January 2018

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Nucleoside analogues previously found to be inactive against HIV may be activated by simple chemical phosphorylation

21 January 2018

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

21 January 2018

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An ELISA utilizing immobilised snowdrop lectin GNA for the detection of envelop glycoproteins of HIV and SIV

21 January 2018

1 reference

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Nucleosides. IX. The Formation of 2',3'-Unsaturated Pyrimidine Nucleosides via a Novel β-Elimination Reaction1,2

21 January 2018

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Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT.

21 January 2018

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10.1016/0014-5793(94)00776-4

21 January 2018

Identifiers

DOI

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30 September 2017

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