Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release. (Q31407508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896673%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release (English)

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8 November 2019

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2

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8 November 2019

author name string

Achenbach TV

series ordinal

1

1 reference

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8 November 2019

Slater EP

series ordinal

3

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8 November 2019

language of work or name

English

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publication date

1 October 2000

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Journal of Biological Chemistry

8 November 2019

published in

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8 November 2019

volume

275

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8 November 2019

issue

41

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8 November 2019

page(s)

32089-32097

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

8 November 2019

cites work

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21 January 2018

Caspases: enemies within

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Caspase knockouts: matters of life and death.

21 January 2018

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The proto-oncogene Bcl-2 and its role in regulating apoptosis

21 January 2018

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The mitochondrial permeability transition pore and its role in cell death

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

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Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

21 January 2018

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Apoptosis and drug response

21 January 2018

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Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

21 January 2018

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Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275

21 January 2018

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Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

21 January 2018

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Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis

21 January 2018

1 reference

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Potent interaction of flavopiridol with MRP1

21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence

21 January 2018

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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

21 January 2018

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

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Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing

21 January 2018

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Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

21 January 2018

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Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

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p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

21 January 2018

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The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

21 January 2018

1 reference

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Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway

21 January 2018

1 reference

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Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

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Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 January 2018

1 reference

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Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

21 January 2018

1 reference

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The bcl-2 gene encodes a novel G protein

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005267200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896673%20AND%20SRC:MED&resulttype=core&format=json

release_4b4x2es5pbak7laypij3p4je74

8 November 2019

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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