RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation (Q32884571)

11 July 2017

RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation (English)

1 reference

Tripartite motif containing 27

11 July 2017

1 reference

ubiquitin protein ligase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

James T Lee

1

1 reference

11 July 2017

Jing Shan

2

1 reference

11 July 2017

Jiayun Zhong

3

1 reference

11 July 2017

Muyang Li

4

1 reference

11 July 2017

Brenda Zhou

5

1 reference

11 July 2017

Amanda Zhou

6

1 reference

11 July 2017

Ramon Parsons

7

1 reference

11 July 2017

Wei Gu

8

1 reference

11 July 2017

19 February 2013

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11 July 2017

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11 July 2017

23

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11 July 2017

552-564

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11 July 2017

4

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https://scigraph.springernature.com/pub.10.1038/cr.2013.27

11 July 2017

0 references

cites work

Minireview: IGF, Insulin, and Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

WWP2 is an E3 ubiquitin ligase for PTEN.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Akt, FoxO and regulation of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Suppression of cancer cell growth by promoting cyclin D1 degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

The emerging complexity of protein ubiquitination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Post-translational regulation of PTEN.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

21 June 2018

New insights into PTEN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

A new mutational AKTivation in the PI3K pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Ubiquitination regulates PTEN nuclear import and tumor suppression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

PCAF modulates PTEN activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Critical nodes in signalling pathways: insights into insulin action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

PTEN function: how normal cells control it and tumour cells lose it

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Mechanisms and consequences of activation of protein kinase B/Akt

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616435

PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

AKT1(E17K) in human solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

RET finger protein expression in invasive breast carcinoma: relationship between RFP and ErbB2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2013.27

The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23419514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of Ret finger protein correlates with outcomes in endometrial cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23419514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Different nuclear/cytoplasmic distributions of RET finger protein in different cell types

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23419514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CR.2013.27

1 reference

Dimensions Publication ID

11 July 2017

0 references

1 reference

11 July 2017

1 reference