Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases (Q33160231)

23 July 2017

title

Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases (English)

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23 July 2017

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Krishna C Chimalakonda

1

1 reference

23 July 2017

Stacie M Bratton

2

1 reference

23 July 2017

Vi-Huyen Le

3

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23 July 2017

Kan Hui Yiew

4

1 reference

23 July 2017

Anna Dineva

5

1 reference

23 July 2017

Cindy L Moran

6

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23 July 2017

Laura P James

7

1 reference

23 July 2017

Jeffery H Moran

8

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23 July 2017

Anna Radominska-Pandya

9

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23 July 2017

publication date

11 July 2011

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Drug Metabolism and Disposition

23 July 2017

published in

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23 July 2017

volume

39

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23 July 2017

issue

10

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23 July 2017

page(s)

1967-1976

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Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine

23 July 2017

cites work

1 reference

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Structure characterisation of urinary metabolites of the cannabimimetic JWH-018 using chemically synthesised reference material for the support of LC-MS/MS-based drug testing

21 June 2018

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21 June 2018

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Spice drugs as a new trend: mode of action, identification and legislation

21 June 2018

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Detection of JWH-018 metabolites in smoking mixture post-administration urine

21 June 2018

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Glucuronidation of dihydrotestosterone and trans-androsterone by recombinant UDP-glucuronosyltransferase (UGT) 1A4: evidence for multiple UGT1A4 aglycone binding sites

21 June 2018

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21 June 2018

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Withdrawal phenomena and dependence syndrome after the consumption of "spice gold"

21 June 2018

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Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation

21 June 2018

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In vitro and in vivo glucuronidation of midazolam in humans

21 June 2018

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Kinetic modeling of the interactions between 4-methylumbelliferone, 1-naphthol, and zidovudine glucuronidation by udp-glucuronosyltransferase 2B7 (UGT2B7) provides evidence for multiple substrate binding and effector sites

21 June 2018

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Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS.

21 June 2018

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Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases

21 June 2018

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21 June 2018

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Human UGT2B7 catalyzes morphine glucuronidation

21 June 2018

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Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves

21 June 2018

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21 June 2018

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Warning: legal synthetic cannabinoid-receptor agonists such as JWH-018 may precipitate psychosis in vulnerable individuals

21 June 2018

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In vitro phase I metabolism of the synthetic cannabimimetic JWH-018.

31 October 2018

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A teenager with agitation: higher than she should have climbed

31 October 2018

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Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.

31 October 2018

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The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes.

31 October 2018

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Resveratrol (trans-resveratrol, 3,5,4'-trihydroxy-trans-stilbene) glucuronidation exhibits atypical enzyme kinetics in various protein sources

31 October 2018

1 reference

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Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186213

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186213

Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases

31 October 2018

1 reference

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Characteristics and problems of 600 adolescent cannabis abusers in outpatient treatment

31 October 2018

1 reference

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Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186213

13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases

31 October 2018

1 reference

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Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromatography-mass spectrometry studies on the metabolism of synthetic cannabinoids JWH-018 and JWH-073, psychoactive components of smoking mixtures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/DMD.111.040709

1 reference

23 July 2017

1 reference

23 July 2017

1 reference