Transient mismatch repair gene transfection for functional analysis of genetic hMLH1 and hMSH2 variants (Q33184847)

23 July 2017

title

Transient mismatch repair gene transfection for functional analysis of genetic hMLH1 and hMSH2 variants (English)

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23 July 2017

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A Brieger

1

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23 July 2017

J Trojan

2

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23 July 2017

J Raedle

3

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23 July 2017

G Plotz

4

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23 July 2017

S Zeuzem

5

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23 July 2017

language of work or name

English

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publication date

1 November 2002

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23 July 2017

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23 July 2017

volume

51

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23 July 2017

issue

5

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23 July 2017

page(s)

677-684

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hMSH3 overexpression and cellular response to cytotoxic anticancer agents

23 July 2017

cites work

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P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin

21 June 2018

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The mismatch repair gene hMSH2 is mutated in the prostate cancer cell line LNCaP.

21 June 2018

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Microsatellite instability in colorectal adenomas: relevance and clinical importance

21 June 2018

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Steady-state regulation of the human DNA mismatch repair system.

21 June 2018

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New directions in the treatment of colorectal cancer: a look to the future

21 June 2018

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MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

21 June 2018

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Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

21 June 2018

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Apoptosis induced by overexpression of hMSH2 or hMLH1.

21 June 2018

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Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine

21 June 2018

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The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer

21 June 2018

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Replication errors: cha(lle)nging the genome

21 June 2018

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Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae

21 June 2018

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Growth suppression mediated by transfection of wild-type hMLH1 in human cancer cells expressing endogenous truncated hMLH1 protein

21 June 2018

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Loss of DNA mismatch repair: effects on the rate of mutation to drug resistance

21 June 2018

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Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6.

21 June 2018

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MutS mediates heteroduplex loop formation by a translocation mechanism

21 June 2018

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Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects

21 June 2018

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Measurement of apoptosis in heterogenous cell populations

21 June 2018

1 reference

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The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs

21 June 2018

1 reference

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Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability

21 June 2018

1 reference

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Purified human MSH2 protein binds to DNA containing mismatched nucleotides

21 June 2018

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GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

21 June 2018

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Avoiding false positives with PCR

21 June 2018

1 reference

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Effects of serum protein and colloid on the alamarBlue assay in cell cultures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773417

Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773417

2-benzoxazolyl and 2-benzimidazolyl hydrazones derived from 2-acetylpyridine: a novel class of antitumor agents

31 October 2018

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Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer.

31 October 2018

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Resistance to topoisomerase poisons due to loss of DNA mismatch repair

31 October 2018

1 reference

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Human mismatch repair and G*T mismatch binding by hMutSalpha in vitro is inhibited by adriamycin, actinomycin D, and nogalamycin

31 October 2018

1 reference

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Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773417

Quantification of mitogen induced human lymphocyte proliferation: comparison of alamarBlue assay to 3H-thymidine incorporation assay

31 October 2018

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Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation

31 October 2018

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12 December 2020

Immunocytochemical detection of hMSH2 and hMLH1 expression in oral melanoma

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12 December 2020

Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae

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12 December 2020

Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer

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12 December 2020

Evaluation of rapid microsatellite analysis of paraffin-embedded specimens in screening for hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

Mediating mismatch repair

1 reference

12 December 2020

Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells

1 reference

12 December 2020

Unbalanced germ-line expression of hMLH1 and hMSH2 alleles in hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.51.5.677

1 reference

23 July 2017

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23 July 2017

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