Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat. (Q33208958)

23 July 2017

Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat. (English)

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23 July 2017

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Regine Schneider-Stock

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Regine Schneider-Stock

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author name string

Matthias Evert

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23 July 2017

Regine Schneider-Stock

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23 July 2017

Frank Dombrowski

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23 July 2017

1 January 2005

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23 July 2017

Laboratory Investigation

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23 July 2017

85

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23 July 2017

1

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23 July 2017

99-108

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https://scigraph.springernature.com/pub.10.1038/labinvest.3700206

23 July 2017

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cites work

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Fatty acid synthase, a proficient multifunctional enzyme

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Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero

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Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells

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Insulin-responsive regions of the rat fatty acid synthase gene promoter.

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Nutritional and hormonal regulation of enzymes in fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription

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Immunohistochemical expression of human erythrocyte glucose transporter and fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue.

21 January 2018

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Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival

21 January 2018

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Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer.

21 January 2018

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The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung

21 January 2018

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Fatty acid synthesis: a potential selective target for antineoplastic therapy

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Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

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Fatty acid synthase: a metabolic oncogene in prostate cancer?

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Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

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Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.

21 January 2018

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Apolipoprotein A-IV mRNA overexpression in early preneoplastic hepatic foci induced by low-number pancreatic islet transplants in streptozotocin-diabetic rats

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The role of SREBP-1c in nutritional regulation of lipogenic enzyme gene expression

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Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

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Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription

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Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

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Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

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Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone

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Human hepatic preneoplasia: phenotypes and proliferation kinetics of foci and nodules of altered hepatocytes and their relationship to liver cell dysplasia

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7 January 2021

Analysis of the IGF axis in preneoplastic hepatic foci and hepatocellular neoplasms developing after low-number pancreatic islet transplantation into the livers of streptozotocin diabetic rats

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Insulin receptor, insulin receptor substrate-1, Raf-1, and Mek-1 during hormonal hepatocarcinogenesis by intrahepatic pancreatic islet transplantation in diabetic rats

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7 January 2021

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

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The human fatty acid synthase gene and de novo lipogenesis are coordinately regulated in human adipose tissue

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Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach

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Fatty acid synthase expression is increased in neoplastic lesions of the oral tongue

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Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients

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OA-519 (fatty acid synthase) as an independent predictor of pathologic state in adenocarcinoma of the prostate

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Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer

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10.1038/LABINVEST.3700206

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23 July 2017

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