One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases (Q33209414)

23 July 2017

title

One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases (English)

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23 July 2017

6

Alexander M M Eggermont

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23 July 2017

1

Dirk J Grünhagen

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23 July 2017

2

Flavia Brunstein

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23 July 2017

4

Albertus N van Geel

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23 July 2017

5

Johannes H W de Wilt

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23 July 2017

3

Wilfried J Graveland

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23 July 2017

language of work or name

English

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publication date

1 December 2004

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23 July 2017

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23 July 2017

volume

240

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23 July 2017

issue

6

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23 July 2017

page(s)

939-47; discussion 947-8

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Current uses of isolated limb perfusion in the clinic and a model system for new strategies

23 July 2017

cites work

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Death receptors and melanoma resistance to apoptosis

31 October 2018

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Factors affecting survival after complete response to isolated limb perfusion in patients with in-transit melanoma

31 October 2018

1 reference

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Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system

31 October 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

31 October 2018

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Systemic toxicity and cytokine/acute phase protein levels in patients after isolated limb perfusion with tumor necrosis factor-alpha complicated by high leakage

31 October 2018

1 reference

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Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion

31 October 2018

1 reference

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Isolated limb perfusion with tumour necrosis factor-alpha and melphalan with or without interferon-gamma for the treatment of in-transit melanoma metastases: a multicentre randomized phase II study.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356509

Complete response of melanoma-in-transit metastasis after isolated limb perfusion with tumor necrosis factor alpha and melphalan without massive tumor necrosis: a clinical and histopathological study of the delayed-type reaction pattern.

31 October 2018

1 reference

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Assessment of the role of neutrophils on the antitumor effect of TNFalpha in an in vivo isolated limb perfusion model in sarcoma-bearing brown Norway rats

31 October 2018

1 reference

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Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience

31 October 2018

1 reference

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Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial

31 October 2018

1 reference

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Treatment of melanoma in-transit metastases confined to the limb.

31 October 2018

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Repeat isolated limb perfusion with melphalan for recurrent melanoma of the limbs.

31 October 2018

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Regional therapy of melanoma

31 October 2018

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Rationale for using TNF alpha and chemotherapy in regional therapy of melanoma

31 October 2018

1 reference

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Long-term morbidity after regional isolated perfusion with melphalan for melanoma of the limbs. The influence of acute regional toxic reactions

31 October 2018

1 reference

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Prognostic variables in recurrent limb melanoma treated with hyperthermic antiblastic perfusion

31 October 2018

1 reference

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High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

31 October 2018

1 reference

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Isolated limb perfusion for melanoma: effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs

31 October 2018

1 reference

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Prognostic factors for survival after isolated limb perfusion for malignant melanoma

31 October 2018

1 reference

12 December 2020

Is there a role for isolated limb perfusion with tumor necrosis factor in patients with melanoma?

1 reference

12 December 2020

Hyperthermic Isolated Limb Perfusion With Low-Dose Tumor Necrosis Factor-α and Melphalan for Bulky In-Transit Melanoma Metastases

1 reference

12 December 2020

Dosimetry in isolation perfusion of the limbs by assessment of perfused tissue volume and grading of toxic tissue reactions

1 reference

12 December 2020

Regional perfusion treatment with melphalan for melanoma in a limb: an evaluation of drug kinetics

1 reference

12 December 2020

Results of regional isolation perfusion with cytostatics in patients with soft tissue tumors of the extremities

1 reference

12 December 2020

Systemic leakage during isolated limb perfusion for melanoma

1 reference

12 December 2020

Prognostic factors for tumor response and limb recurrence-free interval in patients with advanced melanoma of the limbs treated with regional isolated perfusion with melphalan

1 reference

12 December 2020

Treatment of primary or relapsing limb cancer by isolation perfusion with high-dose alpha-tumor necrosis factor, gamma-interferon, and melphalan

1 reference

12 December 2020

Effects of recombinant tumour necrosis factor (rTNF-alpha) in cancer. Observations on the acute phase protein reaction and immunoglobulin synthesis after high dose recombinant TNF-alpha administration in isolated limb perfusions in cancer patients

1 reference

12 December 2020

Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNF alpha)

1 reference

12 December 2020

Cytokine levels and systemic toxicity in patients undergoing isolated limb perfusion with high-dose tumor necrosis factor, interferon gamma, and melphalan

1 reference

12 December 2020

Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study

1 reference

12 December 2020

Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics

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12 December 2020

Relation between limb toxicity and treatment outcomes after isolated limb perfusion for recurrent melanoma

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12 December 2020

Chemotherapy of cancer: regional perfusion utilizing an extracorporeal circuit

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12 December 2020

Regional toxicity after isolated limb perfusion with melphalan and tumour necrosis factor- alpha versus toxicity after melphalan alone

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12 December 2020

10.1097/01.SLA.0000146147.89667.ED

Identifiers

DOI

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23 July 2017

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