Death receptors and melanoma resistance to apoptosis (Q35146582)

6 August 2017

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title

Death receptors and melanoma resistance to apoptosis (English)

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6 August 2017

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3

Ze'ev Ronai

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author name string

Vladimir N Ivanov

series ordinal

1

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PubMed ID

12789291

6 August 2017

Anindita Bhoumik

series ordinal

2

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PubMed ID

12789291

6 August 2017

language of work or name

English

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publication date

1 May 2003

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6 August 2017

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6 August 2017

22

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6 August 2017

20

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6 August 2017

3152-3161

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206456

6 August 2017

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Multiple roles of the tumor suppressor p53.

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Signal transduction by tumor necrosis factor and its relatives

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis

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Frequent downregulation of Fas (CD95) expression and function in melanoma.

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Identification of PTEN mutations in metastatic melanoma specimens

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Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment

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TNF-R1 signaling: a beautiful pathway

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The kiss of death: promises and failures of death receptors and ligands in cancer therapy

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Transcription factors as targets for cancer therapy

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Mutations of the BRAF gene in human cancer

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IAP family proteins--suppressors of apoptosis

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7 January 2021

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

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7 January 2021

Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation

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A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs

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Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10.

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The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization

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Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy

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7 January 2021

The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells

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7 January 2021

Stress-induced decrease in TRAF2 stability is mediated by Siah2

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7 January 2021

The ups and downs of MEK kinase interactions

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7 January 2021

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

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Drug-resistance in human melanoma

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Cellular stress response and apoptosis in cancer therapy.

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How melanoma cells evade trail-induced apoptosis.

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7 January 2021

Transcriptional regulation of the human FasL promoter-enhancer region

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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7 January 2021

NF-kappa B-dependent Fas ligand expression

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7 January 2021

p38 mitogen-activated protein kinase is involved in Fas ligand expression.

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7 January 2021

Death and anti-death: tumour resistance to apoptosis

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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7 January 2021

Cooperation between STAT3 and c-jun suppresses Fas transcription.

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7 January 2021

Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities

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7 January 2021

Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis.

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7 January 2021

Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

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Regulation of Fas-dependent activation-induced T cell apoptosis by cAMP signaling: a potential role for transcription factor NF-kappa B

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Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells

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7 January 2021

p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression

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7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

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7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

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7 January 2021

NF-kappaB at the crossroads of life and death

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

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7 January 2021

Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter

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7 January 2021

Dysregulation of apoptosis genes in hematopoietic malignancies.

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7 January 2021

c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents

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7 January 2021

Apoptosis. A cinderella caspase takes center stage

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7 January 2021

CD95's deadly mission in the immune system

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kappaB

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Breaking the mitochondrial barrier

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

NF-kappaB signals induce the expression of c-FLIP.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

An exegesis of IAPs: salvation and surprises from BIR motifs

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Distinct pattern of p53 phosphorylation in human tumors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Defining CD95 as a tumor suppressor gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Apoptosis by death factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Fas ligand-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The Fas counterattack: cancer as a site of immune privilege

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Fas and Fas ligand interactions suppress melanoma lung metastasis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The biological role of the Fas/FasL system during tumor formation and progression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

ATF2 confers radiation resistance to human melanoma cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

FAP-1: a protein tyrosine phosphatase that associates with Fas

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

A comparative study of Fas and Fas-ligand expression during melanoma progression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Regulation of lymphocyte proliferation and death by FLIP.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

The mitochondrion in apoptosis: how Pandora's box opens

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7 January 2021

TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206456

7 January 2021

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206456

1 reference

6 August 2017

1 reference

PubMed ID

12789291