GPCR antitarget modeling: pharmacophore models for biogenic amine binding GPCRs to avoid GPCR-mediated side effects (Q33213253)

24 July 2017

title

GPCR antitarget modeling: pharmacophore models for biogenic amine binding GPCRs to avoid GPCR-mediated side effects (English)

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G protein-coupled receptor

24 July 2017

main subject

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author name string

Thomas Klabunde

series ordinal

1

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24 July 2017

Andreas Evers

series ordinal

2

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24 July 2017

publication date

1 May 2005

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24 July 2017

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24 July 2017

volume

6

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24 July 2017

issue

5

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24 July 2017

page(s)

876-889

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Drug design strategies for targeting G-protein-coupled receptors

24 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Neuroleptic drug interactions with norepinephrine alpha receptor binding sites in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Ligand design for alpha(1) adrenoceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

A homology-based model of the human 5-HT2A receptor derived from an in silico activated G-protein coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Identification of critical determinants of alpha 1-adrenergic receptor subtype selective agonist binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Ligand-binding modes in cationic biogenic amine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Cloning of the cDNA and gene for a human D2 dopamine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Identification of a single alpha 1-adrenoceptor corresponding to the alpha 1A-subtype in rat submaxillary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha(1) adrenoceptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications for alpha1-adrenoceptor classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Characterization of an α1D‐adrenoceptor mediating the contractile response of rat aorta to noradrenaline

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Characterization of the human dopamine D3 receptor expressed in transfected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

Engineering a region of bulk tolerance in the 5-HT2A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400369

21 January 2018

Identifiers

DOI

10.1002/CBIC.200400369

1 reference

24 July 2017

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