Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys (Q33219678)

24 July 2017

Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys (English)

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24 July 2017

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Nigel L Barnett

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author name string

Chooi-May Lai

1

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24 July 2017

Wei-Yong Shen

2

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24 July 2017

Meliha Brankov

3

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24 July 2017

Yvonne K Y Lai

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24 July 2017

Shu-Yen Lee

6

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24 July 2017

Ian Y S Yeo

7

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24 July 2017

Ranjana Mathur

8

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24 July 2017

Joseph E S Ho

9

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24 July 2017

Paul Pineda

10

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24 July 2017

Amutha Barathi

11

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24 July 2017

Chong-Lye Ang

12

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24 July 2017

Ian J Constable

13

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24 July 2017

Elizabeth P Rakoczy

14

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24 July 2017

1 October 2005

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24 July 2017

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24 July 2017

12

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4

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24 July 2017

659-668

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Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

24 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Levels of vascular endothelial growth factor are elevated in the vitreous of patients with subretinal neovascularisation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Intravitreal sustained release of VEGF causes retinal neovascularization in rabbits and breakdown of the blood-retinal barrier in rabbits and primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Vascular permeability factor, an endothelial cell mitogen related to PDGF

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

The vascular endothelial growth factor family of polypeptides

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Endothelial receptor tyrosine kinases involved in angiogenesis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Periocular gene transfer of sFlt-1 suppresses ocular neovascularization and vascular endothelial growth factor-induced breakdown of the blood-retinal barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Practical considerations of recombinant adeno-associated virus-mediated gene transfer for treatment of retinal degenerations

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Generation of transgenic mice with mild and severe retinal neovascularisation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Preclinical evaluation of a phosphorothioate oligonucleotide in the retina of rhesus monkey

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Gene therapy for ocular angiogenesis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Sustained tetracycline-regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno-associated viral vector

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Gene therapy for ocular neovascularization: a cure in sight

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Expression of cell adhesion molecules and vascular endothelial growth factor in experimental choroidal neovascularisation in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Experimental subretinal neovascularization in the monkey. Permeability of new vessels.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Subretinal neovascularization. Natural history of an experimental model

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

A new view of diabetic retinopathy: a neurodegenerative disease of the eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.04.022

10.1016/J.YMTHE.2005.04.022

7 January 2021

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24 July 2017

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