Pharmacology. Hitting the hot spots of cell signaling cascades (Q33240530)

24 July 2017

Pharmacology. Hitting the hot spots of cell signaling cascades (English)

1 reference

24 July 2017

1 reference

John Joseph Grubb Tesmer

series ordinal

1

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PubMed ID

16627730

24 July 2017

language of work or name

English

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publication date

1 April 2006

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24 July 2017

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24 July 2017

312

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24 July 2017

5772

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24 July 2017

377-378

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

24 July 2017

1 reference

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Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery

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1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Unraveling hot spots in binding interfaces: progress and challenges

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1 reference

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A hot spot of binding energy in a hormone-receptor interface

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1 reference

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Anatomy of hot spots in protein interfaces

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1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues

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1 reference

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Differential targeting of Gbetagamma-subunit signaling with small molecules

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1 reference

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The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

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1 reference

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The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

1 reference

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Sites for Galpha binding on the G protein beta subunit overlap with sites for regulation of phospholipase Cbeta and adenylyl cyclase

21 January 2018

1 reference

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Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits

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1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Exploring protein-protein interactions with phage display

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1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

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1 reference

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Transgenic mice targeting the heart unveil G protein-coupled receptor kinases as therapeutic targets

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1 reference

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1126903

1 reference

24 July 2017

1 reference

PubMed ID

16627730