High epitope expression levels increase competition between T cells (Q33255329)

24 July 2017

title

High epitope expression levels increase competition between T cells (English)

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24 July 2017

3

1 reference

24 July 2017

2

Marcel Salathé

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24 July 2017

Almut Scherer

1

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24 July 2017

publication date

12 July 2006

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PLOS Computational Biology

24 July 2017

published in

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24 July 2017

volume

2

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24 July 2017

issue

8

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24 July 2017

page(s)

e109

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Creative Commons Attribution 4.0 International

24 July 2017

copyright license

start time

18 August 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Impaired processing and presentation of cytotoxic-T-lymphocyte (CTL) epitopes are major escape mechanisms from CTL immune pressure in human immunodeficiency virus type 1 infection

21 June 2018

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

21 June 2018

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Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression

21 June 2018

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Autoreactivity against induced or upregulated abundant self-peptides in HLA-A*0201 following measles virus infection

21 June 2018

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21 June 2018

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Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection

21 June 2018

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Insights into antigen processing gained by direct analysis of the naturally processed class I MHC associated peptide repertoire

21 June 2018

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21 June 2018

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T lymphocyte responses against human parvovirus B19: small virus, big response

21 June 2018

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21 June 2018

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21 June 2018

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Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

21 June 2018

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T cells compete for access to antigen-bearing antigen-presenting cells

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Immunodominance among EBV-derived epitopes restricted by HLA-B27 does not correlate with epitope abundance in EBV-transformed B-lymphoblastoid cell lines

21 June 2018

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Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

21 June 2018

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Quantitative aspects of T cell activation--peptide generation and editing by MHC class I molecules

21 June 2018

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Competition for antigenic sites during T cell proliferation: a mathematical interpretation of in vitro data

21 June 2018

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Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

21 June 2018

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Noncompetitive expansion of cytotoxic T lymphocytes specific for different antigens during bacterial infection.

21 June 2018

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HIV-1 variation diminishes CD4 T lymphocyte recognition.

21 June 2018

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A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells

21 June 2018

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Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection

21 June 2018

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Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice

21 June 2018

1 reference

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

21 June 2018

1 reference

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

21 June 2018

1 reference

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Immunology taught by viruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Minimal requirements for peptide mediated activation of CD8+ CTL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Epitope down-modulation as a mechanism for the coexistence of competing T-cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

CD4+ T cells cross-compete for MHC class II-restricted peptide antigen complexes on the surface of antigen presenting cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

T cell killing does not require the formation of a stable mature immunological synapse.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

HIV evolution: CTL escape mutation and reversion after transmission

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Rapid turnover of T cells in acute infectious mononucleosis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

The race between initial T-helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set-point.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Models of CD8+ responses: 1. What is the antigen-independent proliferation program

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Dynamics of measles virus protein expression are reflected in the MHC class I epitope display

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Competition between MHC class I alleles for cell surface expression alters CTL responses to influenza A virus

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Direct observation of ligand recognition by T cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

T cells down-modulate peptide-MHC complexes on APCs in vivo.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Early programming of T cell populations responding to bacterial infection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Quantification of cell turnover kinetics using 5-bromo-2'-deoxyuridine.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

T cell repertoires and competitive exclusion.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Towards a general function describing T cell proliferation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550274

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

31 October 2018

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12 December 2020

Immunodomination results from functional differences between competing CTL

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12 December 2020

Tolerance and immunity in a mathematical model of T-cell mediated suppression

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12 December 2020

T cell competition for the antigen-presenting cell as a model for immunodominance in the cytotoxic T lymphocyte response against minor histocompatibility antigens

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12 December 2020

Lack of fair play in the T cell response

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12 December 2020

Cutting edge: competition for APC by CTLs of different specificities is not functionally important during induction of antiviral responses

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12 December 2020

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

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12 December 2020

Immunodominance of H60 is caused by an abnormally high precursor T cell pool directed against its unique minor histocompatibility antigen peptide

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12 December 2020

Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models

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12 December 2020

A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo

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12 December 2020

Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant

1 reference

12 December 2020

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

1 reference

12 December 2020

10.1371/JOURNAL.PCBI.0020109

Identifiers

DOI

1 reference

journals/ploscb/SchererSB06

24 July 2017

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

release_kbvvieu5jnfw5j56ixwlymhzxa

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kbvvieu5jnfw5j56ixwlymhzxa

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1550274

1 reference

24 July 2017

1 reference