Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress (Q33259243)

24 July 2017

title

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress (English)

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24 July 2017

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5

David Sidransky

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24 July 2017

Aditi Chatterjee

1

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24 July 2017

Elizabeth Mambo

series ordinal

2

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24 July 2017

Yonggang Zhang

series ordinal

3

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24 July 2017

Theodore Deweese

series ordinal

4

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24 July 2017

language of work or name

English

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publication date

3 October 2006

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24 July 2017

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24 July 2017

volume

6

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24 July 2017

page(s)

235

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Oxidized guanine lesions and hOgg1 activity in lung cancer.

24 July 2017

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Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

21 June 2018

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Mouse models for mitochondrial disease

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Alteration of DNA base excision repair enzymes hMYH and hOGG1 in hydrogen peroxide resistant transformed human breast cells.

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Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

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Leukemic cell line, KG-1 has a functional loss of hOGG1 enzyme due to a point mutation and 8-hydroxydeoxyguanosine can kill KG-1.

21 June 2018

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21 June 2018

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Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein

21 June 2018

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21 June 2018

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Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

21 June 2018

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Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress

21 June 2018

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Effects of nonbulky DNA base damages on Escherichia coli RNA polymerase-mediated elongation and promoter clearance

21 June 2018

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Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours

21 June 2018

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Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

21 June 2018

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21 June 2018

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Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells

21 June 2018

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Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

21 June 2018

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Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase

21 June 2018

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Oxidative damage to DNA: formation, measurement, and biological significance.

21 June 2018

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A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer

21 June 2018

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Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

21 June 2018

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Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue

21 June 2018

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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

21 June 2018

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Mitochondria, free radicals, and neurodegeneration

21 June 2018

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Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

21 June 2018

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Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

21 June 2018

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Repair of products of oxidative DNA base damage in human cells

21 June 2018

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The etiology of breast cancer. Characteristic alteration in hydroxyl radical-induced DNA base lesions during oncogenesis with potential for evaluating incidence risk.

21 June 2018

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Mutagenesis by 8-oxoguanine: an enemy within

21 June 2018

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Oxidants, antioxidants, and the degenerative diseases of aging

21 June 2018

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Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

21 June 2018

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General method for quantifying base adducts in specific mammalian genes

21 June 2018

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Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

21 June 2018

1 reference

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Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli

21 June 2018

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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1633743

Chemical determination of free radical-induced damage to DNA

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1633743

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

21 June 2018

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Interactions of 4-nitroquinoline 1-oxide with deoxyribodinucleotides

21 June 2018

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Inactivation of OGG1 increases the incidence of G . C-->T . A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells.

21 June 2018

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Mutagenicity of a unique 8-oxoguanine in a human Ha-ras sequence in mammalian cells

21 January 2018

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Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria.

21 January 2018

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Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria

21 January 2018

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Quantitative analysis of gene-specific DNA damage in human spermatozoa.

21 January 2018

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Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

21 January 2018

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8-Hydroxyguanosine formed in human lung tissues and the association with diesel exhaust particles

21 January 2018

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12 December 2020

8-oxoguanosine as a marker of neoplastic process in brain

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12 December 2020

Alterations of the DNA repair gene OGG1 in human clear cell carcinomas of the kidney

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12 December 2020

Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction

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12 December 2020

Mutations in the mutY gene of Escherichia coli enhance the frequency of targeted G:C-->T:a transversions induced by a single 8-oxoguanine residue in single-stranded DNA

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12 December 2020

Mitochondrial DNA mutations in epilepsy and neurological disease

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12 December 2020

Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis

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12 December 2020

A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay

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12 December 2020

The type of DNA glycosylase determines the base excision repair pathway in mammalian cells

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12 December 2020

MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae

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12 December 2020

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells

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12 December 2020

Identifiers

DOI

10.1186/1471-2407-6-235

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Dimensions Publication ID

24 July 2017

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1 reference

24 July 2017

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