RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint (Q33260135)

24 July 2017

RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint (English)

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24 July 2017

4

Ellen Fanning

1 reference

24 July 2017

Erin Olson

1

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24 July 2017

Christian J Nievera

series ordinal

2

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24 July 2017

Vitaly Klimovich

series ordinal

3

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24 July 2017

Xiaohua Wu

series ordinal

5

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24 July 2017

language of work or name

English

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publication date

10 October 2006

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Journal of Biological Chemistry

24 July 2017

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24 July 2017

281

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24 July 2017

39517-39533

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24 July 2017

51

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The DNA damage response: putting checkpoints in perspective

24 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Checking on DNA damage in S phase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M605121200

The S phase checkpoint: when the crowd meets at the fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Replication Protein A (RPA): The Eukaryotic SSB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

A dynamic model for replication protein A (RPA) function in DNA processing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Replication protein A phosphorylation and the cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

DNA replication in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Mapping of amino acid residues in the p34 subunit of human single-stranded DNA-binding protein phosphorylated by DNA-dependent protein kinase and Cdc2 kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Phosphorylation of replication protein A by S-phase checkpoint kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Telomerase maintains telomere structure in normal human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Replication protein A (RPA) phosphorylation prevents RPA association with replication centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

ATR Regulates Fragile Site Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

In situ visualization of DNA double-strand break repair in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Immunolocalization in three dimensions: immunogold staining of cytoskeletal and nuclear matrix proteins in resinless electron microscopy sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Recombinant ATM protein complements the cellular A-T phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Chk1 in the DNA damage response: conserved roles from yeasts to mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Constitutive activation of Mek1 by mutation of serine phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605121200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605121200

1 reference

24 July 2017

1 reference