Compound classification using image-based cellular phenotypes (Q33263842)

24 July 2017

Compound classification using image-based cellular phenotypes (English)

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24 July 2017

Cynthia L Adams

1

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24 July 2017

Vadim Kutsyy

2

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24 July 2017

Daniel A Coleman

3

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24 July 2017

Ge Cong

4

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24 July 2017

Anne Moon Crompton

5

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24 July 2017

Kathleen A Elias

6

1 reference

24 July 2017

Donald R Oestreicher

7

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24 July 2017

Jay K Trautman

8

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24 July 2017

Eugeni Vaisberg

9

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24 July 2017

language of work or name

English

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publication date

1 January 2006

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24 July 2017

Methods in Enzymology

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24 July 2017

414

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24 July 2017

440-468

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High content screening applied to large-scale cell biology

24 July 2017

1 reference

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10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin

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Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

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Recruitment of cdc2 kinase by DNA topoisomerase II is coupled to chromatin remodeling

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The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line

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Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro

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Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis

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Switch-of-Function Mutants Based on Morphology Classification of Ras Superfamily Small GTPases

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The action of cytochalasin A on the in vitro polymerization of brain tubulin and muscle G-actin.

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7 January 2021

Functional discovery via a compendium of expression profiles

1 reference

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Microtubules as a target for anticancer drugs

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A functional genomic analysis of cell morphology using RNA interference

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Drug target validation and identification of secondary drug target effects using DNA microarrays

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

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7 January 2021

Multidimensional drug profiling by automated microscopy.

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7 January 2021

Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton

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Structural aspects of Golgi function

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Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

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Making better drugs: Decision gates in non-clinical drug development

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7 January 2021

A gene expression database for the molecular pharmacology of cancer

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7 January 2021

Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D.

1 reference

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7 January 2021

Informatics and quantitative analysis in biological imaging

1 reference

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7 January 2021

An unbiased cell morphology-based screen for new, biologically active small molecules

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7 January 2021

Amylases in the Human Vagina

1 reference

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7 January 2021

An information-intensive approach to the molecular pharmacology of cancer.

1 reference

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7 January 2021

Phenotypic screening of small molecule libraries by high throughput cell imaging

1 reference

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7 January 2021

10.1016/S0076-6879(06)14024-0

Identifiers

DOI

1 reference

24 July 2017

1 reference