Characterization of antibodies in single-chain format against the E7 oncoprotein of the human papillomavirus type 16 and their improvement by mutagenesis. (Q33271188)

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English	Characterization of antibodies in single-chain format against the E7 oncoprotein of the human papillomavirus type 16 and their improvement by mutagenesis.	scientific article

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25 December 2019

Characterization of antibodies in single-chain format against the E7 oncoprotein of the human papillomavirus type 16 and their improvement by mutagenesis (English)

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25 December 2019

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25 December 2019

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Maria Gabriella Donà

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25 December 2019

Colomba Giorgi

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31 January 2007

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25 December 2019

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25 December 2019

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25 December 2019

https://scigraph.springernature.com/pub.10.1186/1471-2407-7-s1-a25

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Engineered antibody fragments and the rise of single domains

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21 June 2018

Combination of Dsb coexpression and an addition of sorbitol markedly enhanced soluble expression of single-chain Fv in Escherichia coli

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21 June 2018

Intracellular anti-E7 human antibodies in single-chain format inhibit proliferation of HPV16-positive cervical carcinoma cells.

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21 June 2018

Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation

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21 June 2018

The intracellular antibody capture technology: towards the high-throughput selection of functional intracellular antibodies for target validation

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21 June 2018

Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering

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21 June 2018

Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo

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21 June 2018

Cervical cancer vaccines: recent advances in HPV research

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21 June 2018

Chapter 1: Human papillomavirus and cervical cancer--burden and assessment of causality

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21 June 2018

Structure-based improvement of the biophysical properties of immunoglobulin VH domains with a generalizable approach

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21 June 2018

Epidemiologic classification of human papillomavirus types associated with cervical cancer

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21 June 2018

Biophysical properties of human antibody variable domains

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21 June 2018

Papillomaviruses and cancer: from basic studies to clinical application

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21 June 2018

The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies

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21 June 2018

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

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21 June 2018

Stability engineering of antibody single-chain Fv fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797048

21 June 2018

Human papillomavirus genotype 16 vaccines for cervical cancer prophylaxis and treatment

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21 June 2018

Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras

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21 June 2018

Extended half-life and elevated steady-state level of a single-chain Fv intrabody are critical for specific intracellular retargeting of its antigen, caspase-7.

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21 June 2018

The mode of action of Y13-259 scFv fragment intracellularly expressed in mammalian cells

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21 June 2018

Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.

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21 June 2018

An integrated vector system for the eukaryotic expression of antibodies or their fragments after selection from phage display libraries

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21 June 2018

Targeting vectors for intracellular immunisation.

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21 June 2018

Determinants of tumor blood flow: a review

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21 June 2018

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

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21 June 2018

Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites

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21 June 2018

Extended half-life upon binding of destabilized intrabodies allows specific detection of antigen in mammalian cells

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31 October 2018

The effect of variable domain orientation and arrangement on the antigen-binding activity of a recombinant human bispecific diabody

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31 October 2018

VL position 34 is a key determinant for the engineering of stable antibodies with fast dissociation rates

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31 October 2018

High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment

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Structural determinants in the sequences of immunoglobulin variable domain

1 reference

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12 December 2020

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In vitro folding and thermodynamic stability of an antibody fragment selected in vivo for high expression levels in Escherichia coli cytoplasm

1 reference

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Nucleocytoplasmic shuttling of antigen in mammalian cells conferred by a soluble versus insoluble single-chain antibody fragment equipped with import/export signals

1 reference

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12 December 2020

based on heuristic

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10.1186/1471-2407-7-S1-A25

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24 July 2017

10.1186/1471-2407-7-25

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25 December 2019

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25 December 2019

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25 December 2019

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