Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation (Q33276827)

25 July 2017

Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation (English)

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25 July 2017

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Yunhong Zhang

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25 July 2017

Tae S Park

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2

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25 July 2017

Jeffrey M Gidday

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3

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25 July 2017

language of work or name

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2 March 2007

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American Journal of Physiology Heart and Circulatory Physiology

25 July 2017

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25 July 2017

292

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6

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25 July 2017

H2573-81

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Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase

25 July 2017

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Spatial and temporal dynamics of the endothelium

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Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

The Protective Effects of Preconditioning on Cerebral Endothelial Cells in Vitro

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Protective effects of preconditioning in cultured rat endothelial cells: effects on neutrophil adhesion and expression of ICAM-1 after anoxia and reoxygenation

21 January 2018

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Hypoxia activates Akt and induces phosphorylation of GSK-3 in PC12 cells

21 January 2018

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Induction of tolerance in rat cortical neurons: hypoxic preconditioning.

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Role of phosphatidylinositol 3-kinase in the development of hepatocyte preconditioning

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Effect of antisense hypoxia-inducible factor 1alpha on progression, metastasis, and chemosensitivity of pancreatic cancer

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Neutrophil-derived glutamate regulates vascular endothelial barrier function

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Survivin-dependent angiogenesis in ischemic brain: molecular mechanisms of hypoxia-induced up-regulation

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Cellular survival: a play in three Akts

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Ischemic preconditioning prevents postischemic arteriolar, capillary, and postcapillary venular dysfunction: signaling pathways mediating the adaptive metamorphosis to a protected phenotype in preconditioned endothelium

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Cerebral microvessel responses to focal ischemia

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Ischemic tolerance and endogenous neuroprotection

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Regulation of survivin function by Hsp90

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Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway

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Cerebral preconditioning and ischaemic tolerance

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Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning

21 January 2018

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Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus

21 January 2018

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Involvement of Akt in preconditioning-induced tolerance to ischemia in PC12 cells.

21 January 2018

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Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease

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VE-cadherin expression and clustering maintain low levels of survivin in endothelial cells

21 January 2018

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Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

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Role of apoptosis-inducing factor in myocardial cell death by ischemia-reperfusion.

21 January 2018

1 reference

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Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Endothelial protective effects of preconditioning.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Role of the Survivin gene in pathophysiology

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Survivin study: an update of "what is the next wave"?

21 January 2018

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Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members

21 January 2018

1 reference

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Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation

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1 reference

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Effect of heat preconditioning on the uptake and permeability of R123 in brain microvessel endothelial cells during mild heat treatment

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Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

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Control of apoptosis during angiogenesis by survivin expression in endothelial cells

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Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity

21 January 2018

1 reference

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Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression

21 January 2018

1 reference

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Ischemic preconditioning attenuates ischemia/reperfusion-induced activation of caspases and subsequent cleavage of poly(ADP-ribose) polymerase in rat hearts in vivo

21 January 2018

1 reference

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Role of Akt signaling in vascular homeostasis and angiogenesis

21 January 2018

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The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

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Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway

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Survivin: a protein with dual roles in mitosis and apoptosis

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Tumor-specific gene expression using the survivin promoter is further increased by hypoxia

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01098.2006

Cerebral endothelial cell apoptosis after ischemia-reperfusion: role of PARP activation and AIF translocation.

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1 reference

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Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

21 January 2018

1 reference

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10.1152/AJPHEART.01098.2006

21 January 2018

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25 July 2017

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